PMID: 9420745Nov 1, 1994Paper

Thallium 201 for detection of viable myocardium: comparison of different reinjection protocols

Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology
L FavaroG Botti

Abstract

The finding fo false fixed 201Tl defects by the conventional stress-redistribution protocol is a well-known phenomenon. The aim of this study was to compare two different 201Tl reinjection protocols to identify viable myocardium in the same group of patients. Twenty-seven patients with ischemic heart disease and at least one persistent defect on 201Tl uptake redistribution images 3 hours after stress were investigated. In the same-day protocol (R1) patients were reinjected with 1 mCi 201Tl immediately after redistribution images, with imaging starting 15 minutes later; in the different-day protocol the patients were reinjected with 2 mCi 48 to 96 hours later. Two sets of images were obtained, 30 (R2) and 180 (R3) minutes after reinjection. The comparison of redistribution and reinjection versus stress images showed a significant (p < 0.01) frequency distribution. The uptake of 201Tl of the 111 irreversible segments at redistribution was enhanced in 35.1% with R1, 43.2% with R2, and 49.5% with R3. The agreement among the three procedures in classifying the segmental defects was high between R2 and R3 (r = 0.81) and lower between the same- and different-day protocols. Of the 19 patients with a dominant scar pattern demonstrated b...Continue Reading

References

Jul 1, 1991·Seminars in Nuclear Medicine·R O Bonow, V Dilsizian
Feb 1, 1990·Journal of the American College of Cardiology·L D YangJ Maddahi
Feb 1, 1990·Journal of the American College of Cardiology·E H Botvinick
Sep 1, 1989·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·N B SchillerI Schnittger
Dec 1, 1988·Journal of the American College of Cardiology·H KiatJ Friedman
Apr 3, 1986·The New England Journal of Medicine·J TillischH Schelbert
May 1, 1994·European Journal of Nuclear Medicine·E M DudzicA Lahiri
Sep 4, 2008·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Ebere O ChukwuAasha S Gopal

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