PMID: 9179552May 1, 1997Paper

The 13C-mixed triglyceride breath test in healthy adults: determinants of the 13CO2 response

European Journal of Clinical Investigation
M KalivianakisR J Vonk

Abstract

Defects in lipolysis due to pancreatic insufficiency can be diagnosed by the mixed triglyceride (MTG) 13CO2 breath test. However, the effects of various test conditions on the 13CO2 response have only been partially elucidated. In healthy adults, we performed the 13CO2 mixed triglyceride breath test and we compared (a) the inter- and intra-individual variation in the 13CO2 response; (b) the effect of two different test meals; (c) the effect of an additional meal during the test; and (d) the effect of physical exercise during the test. Upon repeating the test in the same individual (test meal cream), repeatability coefficients were large, with respect to either time to maximum 13C excretion rate (3.8 h). maximum 13C excretion rate (4.9% 13C dose h-1) or cumulative recovery of 13C over the 9-h study period (22.7% 13C dose). The cumulative 13C expiration over 9 h obtained with the test meal composed of cream was quantitatively similar to that obtained with bread and butter: 42.2 +/- 8.4% and 47.7 +/- 6.3% respectively. Fasting for 9 h during the test resulted in similar 13C expiration rates and cumulative 13C expiration (43.4% +/- 7.2%) when compared with consumption of an additional meal 3 h after the start of the test (38.3 +/- ...Continue Reading

Citations

Oct 24, 1998·Nutrition·L T Weaver
Jul 8, 2011·The British Journal of Nutrition·Małgorzata BożekMonika Piłka
Mar 18, 2006·Isotopes in Environmental and Health Studies·Frans Stellaard, Henk Elzinga
Aug 6, 1999·Journal of Pediatric Gastroenterology and Nutrition·K D WutzkeW E Heine
Mar 12, 2004·Journal of Gastroenterology and Hepatology·Marc A RitzGeoff Davidson
Oct 15, 1998·Archives of Disease in Childhood·J L MurphyS A Wootton
Mar 20, 1999·Gut·L T WeaverG R Swart
Jun 10, 2009·Best Practice & Research. Clinical Gastroenterology·Barbara Braden
Aug 19, 2008·Clinica Chimica Acta; International Journal of Clinical Chemistry·Caterina AnaniaClaudio Chiesa
Aug 31, 2007·European Journal of Clinical Investigation·A R J SchneiderJ Stein
Jun 17, 2015·Current Treatment Options in Gastroenterology·Phil A Hart, Darwin L Conwell
Jan 11, 2018·Journal of Inherited Metabolic Disease·D-J Reijngoud
Aug 31, 2016·World Journal of Gastrointestinal Pathophysiology·Imran SiddiquiShahab Abid
Jun 12, 2004·American Journal of Physiology. Gastrointestinal and Liver Physiology·L K BryantR Butler
Jun 23, 2011·Journal of Pediatric Gastroenterology and Nutrition·Els Van de VijverGigi Veereman-Wauters
Nov 30, 2006·Journal of Pediatric Gastroenterology and Nutrition·Christine SlaterLawrence T Weaver
Feb 9, 2005·Journal of Pediatric Gastroenterology and Nutrition·Jaroslaw WalkowiakJohn A Dodge
Dec 7, 2005·Rapid Communications in Mass Spectrometry : RCM·Christine SlaterLawrence T Weaver
Apr 29, 2015·Journal of Pediatric Gastroenterology and Nutrition·Christopher J TaylorMichael Wilschanski
Aug 3, 2020·Current Opinion in Gastroenterology·J Enrique Dominguez-Muñoz
Oct 15, 1998·The British Journal of Nutrition·S AmarriL T Weaver
Nov 7, 2018·World Journal of Gastrointestinal Pharmacology and Therapeutics·Benjamin Myles ShandroAndrew Poullis

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