The 2-stage hypospadias repair. Is it a misnomer?

The Journal of Urology
Aseem R ShuklaD A Canning

Abstract

The repair of penoscrotal or perineal hypospadias with severe chordee may require division of the urethral plate to facilitate repair. While a 2-stage approach to these difficult cases has been advocated, we have used a modified tubularized transverse preputial island flap (TPIF) repair as a 1-stage procedure. We compare our results with both procedures. Between 1997 and 2001, 1 surgeon (DAC) performed 22 penoscrotal or scrotal hypospadias repairs that required transection of the urethral plate. A TPIF or planned 2-stage repair was done in 12 and 10 boys, respectively. The TPIF was modified by suturing the medial edge of the island flap along the length of the corpora recreating a urethral plate and then tubularizing a neourethra. The 2-stage approach consisted first of mobilizing skin to the ventrum of the penis followed 6 to 12 months later by a urethroplasty. At followup cosmetic and functional results were assessed. The TPIF and staged repair groups have been followed for a mean 24.5 and 43.5 months following the first repair, respectively. Of the 12 boys undergoing a TPIF 2 (16.7%) required a fistula repair or meatoplasty while 7 of 10 (70%) required at least 1 additional operation after the stage 2 urethroplasty (p <0.05)...Continue Reading

References

Jan 1, 1991·European Urology·P A DewanP G Ransley
Aug 1, 1994·The Journal of Urology·S P GreenfieldJ Wan
Aug 1, 1994·The Journal of Urology·A B RetikA Atala
Aug 12, 1999·BJU International·A Elbakry
Mar 29, 2000·The Journal of Urology·C R PowellG W Kaplan
May 8, 2000·The Journal of Urology·T F Kolon, E T Gonzales
May 25, 2002·International Journal of Urology : Official Journal of the Japanese Urological Association·Kentaro MizunoKenjiro Kohri

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Citations

Nov 10, 2007·Der Urologe. Ausg. A·M Westenfelder, C Möhring
Aug 7, 2013·Nature Reviews. Urology·Marcello CimadorMarco Castagnetti
Aug 27, 2014·Clinics in Perinatology·Lauren BaldingerAseem R Shukla
Sep 15, 2005·The Kaohsiung Journal of Medical Sciences·Yung-Chin LeeWen-Jeng Wu
Jun 16, 2012·The Journal of Urology·Jeremy B MyersBenjamin N Breyer
Jul 6, 2010·Journal of Pediatric Urology·Warren Snodgrass, Nicol Bush
Apr 23, 2010·International Journal of Urology : Official Journal of the Japanese Urological Association·Rajendra NerliMurigendra Hiremath
Feb 16, 2006·European Urology·Guido BarbagliMassimo Lazzeri
Feb 9, 2006·European Urology·Navroop S JohalPeter M Cuckow
May 13, 2015·The Journal of Urology·Erin R McNamaraMarc Cendron
Aug 10, 2015·Current Urology Reports·Warren Snodgrass, Nicol Bush
Apr 30, 2011·Journal of Pediatric Urology·Antonio MacedoValdemar Ortiz
Jun 1, 2013·Arab Journal of Urology·Haytham Badawy, Ahmed Fahmy
Oct 30, 2020·Research and Reports in Urology·Johannes AritonangGerhard Reinaldi Situmorang

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