PMID: 18407157Aug 1, 1993Paper

The 3beta-hydroxysteroid dehydrogenase gene family of enzymes

Trends in Endocrinology and Metabolism : TEM
J Ian Mason

Abstract

It now is apparent that a family of closely related genes encode for 3beta- hydroxysteroid dehydrogenase (3betaHSD). Studies on the regulation of these genes are in their infancy, but the regulation appears multifactorial. The various 3betaHSD genes are expressed principally in a tissue-specific manner likely involving separate mechanisms of regulation. To date, two human 3betaHSD genes and their products have been characterized; type I is expressed in placenta, sebaceous glands, and several other nonendocrine tissues, whereas the type II isoform is the principal 3betaHSD of adrenal cortex and gonads.

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Citations

Apr 1, 1996·Cellular and Molecular Neurobiology·E E BaulieuY Akwa
Dec 1, 1993·The Journal of Steroid Biochemistry and Molecular Biology·J I MasonM M Ralph
Jun 1, 1995·The Journal of Steroid Biochemistry and Molecular Biology·J SimardF Labrie
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