The Ability of Dual-Energy Computed Tomography to Distinguish Normal Bone Marrow From Metastases Using Bone Marrow Color Maps

Journal of Computer Assisted Tomography
Ghada IssaMichael E Mulligan

Abstract

The objective of this study was to determine if dual-energy computed-tomography bone marrow color maps can improve sensitivity, specificity, accuracy, and confidence of detection of bone metastases. Institutional review board approved this retrospective review of a consecutive series of cancer patients. Two radiologists first evaluated the fused 120 kV computed tomography images and recorded a number of suspicious lesions, confidence level, and Hounsfield units for each lesion. After a time gap, the studies were randomized for a second review with dual-energy computed-tomography bone marrow color maps. Eighteen patients and 1105 bones were reviewed. A total of 227 true metastatic lesions were present. With bone marrow color map review, sensitivity increased from 76.2% to 86.8%, for reader 1, and from 80.2% to 92.8%, for reader 2. Specificity and accuracy also increased. Confidence level increased for 12 lesions. Dual-energy computed-tomography bone marrow color map analysis of patients with metastatic cancers can improve the sensitivity, specificity, accuracy, and confidence level for the detection of bone metastases.

References

Jul 16, 2010·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Courtney A CourseySebastian T Schindera
Nov 1, 2012·AJR. American Journal of Roentgenology·Savvakis NicolaouPeter Munk
Jul 18, 2014·Journal of Computer Assisted Tomography·Jijo PaulEmmanuel C Mbalisike
Feb 26, 2015·AJR. American Journal of Roentgenology·Christoph ThomasMarius Horger
Aug 25, 2015·Radiology·Cynthia H McColloughJoel G Fletcher
Apr 22, 2016·AJR. American Journal of Roentgenology·Adam UlanoConnie Y Chang
Nov 22, 2016·Radiology·Paul I MallinsonHugue A Ouellette

❮ Previous
Next ❯

Citations

Jan 11, 2021·Seminars in Roentgenology·Francis I Baffour, Katrina N Glazebrook

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cancer Imaging

Imaging techniques, including CT and MR, have become essential to tumor detection, diagnosis, and monitoring. Here is the latest research on cancer imaging.