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The ABO blood group is a trans-species polymorphism in primates

Proceedings of the National Academy of Sciences of the United States of America

Oct 24, 2012

Laure SégurelMolly Przeworski

Abstract

The ABO histo-blood group, the critical determinant of transfusion incompatibility, was the first genetic polymorphism discovered in humans. Remarkably, ABO antigens are also polymorphic in many other primates, with the same two amino acid changes responsible for A and B specificity in ...read more

Mentioned in this Paper

ABO gene
Hylobates Genus
Recurrent Malignant Neoplasm
Major Histocompatibility Complex
Major Histocompatibility Complex Location
Mini-Exon
ABO Blood Group System
Antigens
Evolution, Molecular
Phylogeny
97
3
5
126
1
2
Paper Details
References
  • References40
  • Citations43
1234
  • References40
  • Citations43
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The ABO blood group is a trans-species polymorphism in primates

Proceedings of the National Academy of Sciences of the United States of America

Oct 24, 2012

Laure SégurelMolly Przeworski

PMID: 23091028

DOI: 10.1073/pnas.1210603109

Abstract

The ABO histo-blood group, the critical determinant of transfusion incompatibility, was the first genetic polymorphism discovered in humans. Remarkably, ABO antigens are also polymorphic in many other primates, with the same two amino acid changes responsible for A and B specificity in ...read more

Mentioned in this Paper

ABO gene
Hylobates Genus
Recurrent Malignant Neoplasm
Major Histocompatibility Complex
Major Histocompatibility Complex Location
Mini-Exon
ABO Blood Group System
Antigens
Evolution, Molecular
Phylogeny
97
3
5
126
1
2

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Paper Details
References
  • References40
  • Citations43
1234
  • References40
  • Citations43
12345
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