PMID: 6360747Jan 1, 1983Paper

The acceptability of a non-benzodiazepine hypnotic (Zopiclone) in general practice

The Journal of International Medical Research
P J ChaudoirG J Wilcox


The hypnotic effects of Zopiclone, a novel cyclopyrrolone derivative, were compared with placebo in a double-blind randomized crossover study in insomniac patients. Subjective morning assessments by the patients showed that Zopiclone 7.5 mg improved the quality of sleep, with a reduction in the sleep onset latency and the number of nocturnal awakenings. Zopiclone was judged by the physicians to be superior to placebo and was preferred by the patients. Subjective residual effects and adverse reactions were minimal.


Jul 1, 1979·British Journal of Clinical Pharmacology·M Hills, P Armitage
Sep 15, 1978·Science·A KalesJ D Kales
Sep 28, 1973·Psychopharmacologia·A J Bond, M H Lader
Sep 5, 1981·British Medical Journal·H Petursson, M H Lader
Jan 1, 1983·Pharmacology·A N Nicholson, B M Stone
Jul 10, 1982·British Medical Journal·A N Nicholson, M B Spencer
Mar 1, 1980·British Journal of Clinical Pharmacology·A N Nicholson


Jan 1, 1986·Acta Psychiatrica Scandinavica. Supplementum·D Wheatley
Mar 1, 1988·Canadian Journal of Psychiatry. Revue Canadienne De Psychiatrie·J A FlemingP Hamilton
Mar 1, 1986·Biopharmaceutics & Drug Disposition·L LarivièreR Elie
Mar 1, 1985·The British Journal of Psychiatry : the Journal of Mental Science·D Wheatley
Aug 5, 2015·Behavioral Sleep Medicine·Janet M Y CheungBandana Saini

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Zopiclon von ct
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