The accumulation of P-elements on the tip of the X chromosome in populations of Drosophila melanogaster

Genetical Research
J W Ajioka, W F Eanes

Abstract

Little information exists about the mechanisms that determine the fate of mobile elements in natural populations. In this study we catalogue the distribution of 638 P-elements across 114 X chromosomes in samples drawn from three natural populations of Drosophila melanogaster. There is an extremely high occurrence of elements at the tip relative to the rest of the euchromatic chromosome. We demonstrate that the distribution of de novo insertions of the P-element on a specific laboratory chromosome is markedly different; no P-elements were recovered at the tip in the 243 insertion events recorded. In contrast, insertion data for the pi2 chromosome suggests an elevated rate associated with the tip site although it does not appear sufficient to explain the large differential accumulation on wild chromosomes. This raises the issue of inter chromosome (or tip) variation in relative rates, as well as the possibility that rates of elimination are lower at the tip.

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Citations

Sep 13, 1994·Proceedings of the National Academy of Sciences of the United States of America·D Thompson-StewartA C Spradling
Jan 19, 2008·Genetics·Jennifer A AndersonCharles H Langley
Jan 1, 1994·Genetica·N ParicioR de Frutos
Nov 1, 1995·Biochimica Et Biophysica Acta·D D LasicY Barenholz
Mar 14, 2012·G3 : Genes - Genomes - Genetics·Maria PöyhönenStéphane Ronsseray
Dec 1, 1989·European Journal of Epidemiology·H Krauss
Oct 31, 2018·PLoS Biology·Colin D Meiklejohn, Justin P Blumenstiel
Dec 9, 2021·Molecular Ecology·Filip WierzbickiSarah Signor

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