The accuracy and efficacy of real-time continuous glucose monitoring sensor in patients with type 1 diabetes

Diabetes Technology & Therapeutics
John MastrototaroSTAR 1 Clinical Trial Investigators

Abstract

The accuracy and efficacy of the Medtronic Diabetes (Northridge, CA) Real-Time (RT)-Continuous Glucose Monitoring (CGM) sensor were analyzed in 72 subjects with type 1 diabetes. This was a retrospective analysis of 60,050 temporally paired data points (sensor and glucose meter values) obtained during the course of an outpatient ambulatory study evaluating the efficacy of a sensor-augmented pump system in adults and adolescents. Subjects uploaded sensor values and self-monitoring blood glucose data to the CareLink Clinical Application (Medtronic Diabetes) via the Internet, every 2 weeks during the course of the study. The overall percentage of sensor readings within +/-20% or +/-30% agreement of reference glucose readings was 75.6% and 86.8%, respectively. The highest rate of agreement occurred in the 240-400 mg/dL range, where 79.9% of sensor readings were within +/-20% of meter values and 91.5% of sensor readings were within 30% of meter values. The mean absolute relative difference for all subjects was 15.8%, and the median absolute relative difference was 10.9%. The bias was -2.13 mg/dL. Paired glucose measurements from the RT-CGM and meter demonstrated that 95.9% of paired points in the overall subject population fell in zo...Continue Reading

Associated Clinical Trials

References

Mar 29, 2002·Diabetes/metabolism Research and Reviews·Russell O PottsMichael J Tierney
Dec 28, 2002·Diabetes Care·Saul GenuthUNKNOWN American Diabetes Association
Mar 28, 2003·BMC Health Services Research·Alyce S AdamsDennis Ross-Degnan
Aug 27, 2005·Diabetes Technology & Therapeutics·Julie WagnerGina Abbott
Dec 29, 2006·Diabetes Care·Darrell M WilsonUNKNOWN DirecNet Study Group

❮ Previous
Next ❯

Citations

Aug 29, 2012·Endocrine·Nelly MaurasRoy W Beck
Oct 24, 2013·European Journal of Clinical Nutrition·Ç S KasapkaraL Tümer
Jul 21, 2009·Diabetes Technology & Therapeutics·Jim Brauker
Jul 21, 2009·Diabetes Technology & Therapeutics·Anne Peters
Jul 21, 2009·Diabetes Technology & Therapeutics·Jay S Skyler
Jun 11, 2010·Diabetes Technology & Therapeutics·David Kerr, Tolu Olateju
Dec 14, 2011·Diabetes Technology & Therapeutics·Katherine E IscoePaul A Fournier
Dec 8, 2011·Diabetes Technology & Therapeutics·Desmond Barry KeenanRajiv V Shah
Apr 20, 2012·Diabetes Technology & Therapeutics·Thomas ZuegerChristoph Stettler
Mar 21, 2012·Diabetes Technology & Therapeutics·Peter AdolfssonJohan Jendle
Nov 10, 2012·Diabetes Technology & Therapeutics·Jane E YardleyBruce A Perkins
Dec 14, 2012·Diabetes Technology & Therapeutics·Ahmed El-LaboudiDesmond Johnston
May 9, 2013·Diabetes Technology & Therapeutics·Yoeri M LuijfUNKNOWN AP@home consortium
Nov 11, 2011·The American Journal of Clinical Nutrition·Anthony N FabricatoreDavid S Ludwig
Apr 15, 2009·Biomedical Papers of the Medical Faculty of the University Palacký, Olomouc, Czechoslovakia·Karolina PetersonRudolf Chlup
Jul 7, 2011·Expert Review of Medical Devices·Eda CengizWilliam V Tamborlane
Jan 1, 2013·Diagnostics·Sandeep Kumar Vashist
Sep 1, 2011·Diabetes Research and Clinical Practice·Andriani Vazeou
Jul 8, 2009·Drug Discovery Today·Jennifer SherrWilliam V Tamborlane
Mar 10, 2009·Diabetes/metabolism Research and Reviews
Sep 15, 2012·Diabetes, Obesity & Metabolism·E ZijlstraS Heckermann
Feb 4, 2010·Diabetic Medicine : a Journal of the British Diabetic Association·C WeiR Hovorka
Apr 23, 2013·Diabetes, Obesity & Metabolism·P A BakhtianiW K Ward
Jun 12, 2010·Diabetic Medicine : a Journal of the British Diabetic Association·D ElleriR Hovorka
Jul 3, 2013·Orvosi hetilap·Gábor MaricsPéter Tóth-Heyn
Oct 17, 2016·Analytical and Bioanalytical Chemistry·Sanjiv SharmaAnthony E G Cass
Jan 10, 2012·Journal of Diabetes Science and Technology·D Barry KeenanJohn J Mastrototaro
Sep 2, 2011·Journal of Diabetes Science and Technology·Cynthia R MarlingFrank L Schwartz
Jul 5, 2011·Journal of Diabetes Science and Technology·Douglas MuchmoreDaniel Vaughn
Oct 6, 2010·Journal of Diabetes Science and Technology·Kerstin RebrinGarry M Steil
May 31, 2014·Journal of Diabetes Science and Technology·Uwe BeyerLutz Heinemann
May 31, 2014·Journal of Diabetes Science and Technology·Sandra I SobelFrederico G S Toledo
Aug 1, 2015·Journal of Diabetes Science and Technology·Andrew DehennisSorin Ioacara
Jun 10, 2015·Journal of Diabetes Science and Technology·Zeinab MahmoudiOle Hejlesen
Jul 18, 2014·Journal of Diabetes Science and Technology·Venkat Sasidhar RenukuntlaRubina A Heptulla
Jul 20, 2014·Journal of Diabetes Science and Technology·David Rodbard

❮ Previous
Next ❯

Related Concepts

Related Feeds

Autoimmune Diabetes & Tolerance

Patients with type I diabetes lack insulin-producing beta cells due to the loss of immunological tolerance and autoimmune disease. Discover the latest research on targeting tolerance to prevent diabetes.