The Accuracy of Prostate Magnetic Resonance Imaging Interpretation: Impact of the Individual Radiologist and Clinical Factors

Urology
Nicholas A PickersgillEric H Kim

Abstract

To compare test performance of multiparametric magnetic resonance imaging (mpMRI) for detection of prostate cancer between individual radiologists using the Prostate Imaging Reporting and Data System (PI-RADS) and to identify clinical factors that may predict test performance. We examined our database of consecutive men who received prostate mpMRI prior to biopsy between September 2014 and December 2016 (n = 459). Test performance (eg, sensitivity, specificity, positive predictive value [PPV] and negative predictive value) were defined with PI-RADS classification 4 or 5 considered test positive and Gleason score ≥7 on biopsy from any targeted core considered outcome positive. Multivariate logistic regression was performed to identify clinical variables that affect test performance. No significant differences in test performance were found among individual radiologists. Prior biopsy (odds ratio [OR] 0.10, P = .01), radiologist experience >500 prostate mpMRI (OR 0.18, P = .04), transition zone location (OR 0.10, P = .04), and posterior location (OR 0.04, P = .03) were predictors of diminished sensitivity. Location of the mpMRI lesion in the TZ was a predictor of improved specificity (OR 2.53, P = .04). Increasing age (OR 1.07, P ...Continue Reading

Citations

Nov 2, 2019·Journal of Magnetic Resonance Imaging : JMRI·Nicola Schieda
Jan 28, 2021·AJR. American Journal of Roentgenology·Renato CuocoloArnaldo Stanzione
Feb 27, 2021·Therapeutic Advances in Urology·B M Zeeshan HameedBhavan Prasad Rai
Apr 27, 2021·European Urology Open Science·Hyunseon C KangHaesun Choi
Mar 28, 2021·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Russell K PachynskiJames J Hsieh

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