The accuracy of sentinel lymph node biopsy in the treatment of multicentric invasive breast cancer using a subareolar injection of tracer.

World Journal of Surgery
Calogero CipollaMario A Latteri

Abstract

The aim of this study was to evaluate the feasibility and the accuracy of sentinel lymph node biopsy in multicentric breast cancer (MBC) performed by means of a subareolar (SA) injection of both 99Tc-labeled human albumin colloid and lymphazurin. Between January 2002 and October 2007, 34 patients with MBC with clinically negative axilla underwent sentinel lymph node biopsy (SLNB) followed by total axillary node dissection (AD). Overall successful identification rate of SLN was 100%; there were no false negatives and overall accuracy rate was 100%. The mean number of sentinel lymph nodes (SLNs) identified was 1.8 +/- 0.88 (range = 1-4); the mean number of axillary lymph nodes examined was 21.4 +/- 5.76 (range = 8-36). The authors conclude that SA injection of the tracer is feasible and efficacious in the identification of the SLN. The accuracy of SLNB in MBC is comparable to that obtained in unifocal disease.

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Citations

Jan 22, 2010·World Journal of Surgical Oncology·Alessandra MascaroLucio Fortunato
Jan 21, 2014·Revista española de medicina nuclear e imagen molecular·I Blanco SaizF J Aira Delgado
Feb 5, 2011·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·A J Spillane, M E Brennan
Jul 10, 2010·Surgical Oncology·Sofiane BendifallahRoman Rouzier
Jul 14, 2010·Surgical Oncology Clinics of North America·Bijan Ansari, Judy C Boughey
Feb 26, 2013·The British Journal of Surgery·Y AnderssonL Bergkvist
May 20, 2015·Gynécologie, obstétrique & fertilité·G HouvenaeghelE Lambaudie
Apr 30, 2015·Gynécologie, obstétrique & fertilité·R MosbahO Graesslin
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Dec 1, 2012·Breast Care·Vikram SwaminathanRiccardo A Audisio
May 19, 2011·Journal of Computer Assisted Tomography·Hongna TanWeijun Peng

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