PMID: 28498827May 13, 2017Paper

The Accuracy of the Spot Sign and the Blend Sign for Predicting Hematoma Expansion in Patients with Spontaneous Intracerebral Hemorrhage

Medical Science Monitor : International Medical Journal of Experimental and Clinical Research
Jun ZhengChao You

Abstract

BACKGROUND Hematoma expansion is associated with poor outcome in intracerebral hemorrhage (ICH) patients. The spot sign and the blend sign are reliable tools for predicting hematoma expansion in ICH patients. The aim of this study was to compare the accuracy of the two signs in the prediction of hematoma expansion. MATERIAL AND METHODS Patients with spontaneous ICH were screened for the presence of the computed tomography angiography (CTA) spot sign and the non-contrast CT (NCCT) blend sign within 6 hours after onset of symptoms. The sensitivity, specificity, and positive and negative predictive values of the spot sign and the blend sign in predicting hematoma expansion were calculated. The accuracy of the spot sign and the blend sign in predicting hematoma expansion was analyzed by receiver-operator analysis. RESULTS A total of 115 patients were enrolled in this study. The spot sign was observed in 25 (21.74%) patients, whereas the blend sign was observed in 22 (19.13%) patients. Of the 28 patients with hematoma expansion, the CTA spot sign was found on admission CT scans in 16 (57.14%) and the NCCT blend sign in 12 (42.86%), respectively. The sensitivity, specificity, positive predictive value, and negative predictive value o...Continue Reading

References

Aug 1, 1996·Stroke; a Journal of Cerebral Circulation·R U KothariJ Khoury
Apr 26, 2006·Neurology·S M DavisUNKNOWN Recombinant Activated Factor VII Intracerebral Hemorrhage Trial Investigators
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Feb 1, 2014·Stroke; a Journal of Cerebral Circulation·David Rodriguez-LunaUNKNOWN PREDICT/Sunnybrook ICH CTA Study Group
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Nov 6, 2014·Journal of Korean Neurosurgical Society·Ju-Hee HanHa-Young Choi
Apr 29, 2015·International Journal of Stroke : Official Journal of the International Stroke Society·Sheila ChanAlexander C Flint
Oct 10, 2015·Stroke; a Journal of Cerebral Circulation·Dylan BlacquiereUNKNOWN PREDICT/Sunnybrook ICH CTA Study Group
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Feb 6, 2016·Stroke; a Journal of Cerebral Circulation·Dar DowlatshahiMukul Sharma

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Citations

Jun 27, 2018·Acta neurochirurgica·Peter B SpornsWalter Heindel
Jul 6, 2019·Stroke; a Journal of Cerebral Circulation·Thanh G PhanHenry Ma
Aug 1, 2019·Annals of Neurology·Andrea MorottiUNKNOWN International NCCT ICH Study Group
Feb 23, 2021·Clinical Neurology and Neurosurgery·Christiane FranzOmid Nikoubashman
Nov 30, 2021·International Journal of Stroke : Official Journal of the International Stroke Society·Francesco ArbaAndrea Morotti

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