The accuracy of transcranial Doppler in the diagnosis of stenosis or occlusion of the terminal internal carotid artery

Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging
Jose C NavarroAndrei V Alexandrov

Abstract

Transcranial Doppler (TCD) can detect intracranial stenoses and occlusions that can help in the diagnosis and management of ischemic stroke. The accuracy parameters for lesions located in the terminal internal carotid artery (TICA) are less known, unlike other basal cerebral vessels. The authors studied consecutive patients referred for TCD who underwent contrast angiography or magnetic resonance angiography. They calculated the sensitivity, specificity, positive and negative predictive values (PPV and NPV), and likelihood ratios. Forty-three patients had TCD and angiography: mean age was 57 +/- 20 years, and 65% were men. Twenty-two patients were diagnosed with TICA stenosis or occlusion on TCD underwent angiography. Four patients had abnormal TCD findings that were not confirmed by angiography. Two of 21 patients with normal TCD showed moderate (< 50%) stenosis of the TICA and cavernous segment of the internal carotid artery at angiography. Accuracy parameters for TCD were as follows: sensitivity = 90% (confidence interval [CI], 63%-96%), specificity = 83% (CI, 61%-94%), PPV = 82%, NPV = 86%, positive likelihood ratio = 5, and negative likelihood ratio = 0.17. TCD is a sensitive screening tool for the lesions in the TICA. Spe...Continue Reading

Citations

Apr 25, 2007·Vascular Medicine·Eric R BatesUNKNOWN Society for Interventional Radiology
Aug 19, 2008·International Journal of Stroke : Official Journal of the International Stroke Society·Lawrence K S Wong
Feb 4, 2009·Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging·Qing HaoKa Sing Wong
Oct 8, 2009·Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging·Edward Feldmann
Nov 6, 2009·Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging·Yong YouKa Sing Wong
Sep 15, 2009·Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging·Gustavo J RodriguezAdnan I Qureshi

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