PMID: 8602337Aug 1, 1995Paper

The action of thymol on oral bacteria

Oral Microbiology and Immunology
S Shapiro, B Guggenheim

Abstract

Several effects of thymol, a plant-derived antimicrobial agent, on Porphyromonas gingivalis, Selenomonas artemidis and Streptococcus sobrinus were examined. The extremely rapid efflux of intracellular constituents evoked by thymol is consistent with its postulated membranotropic effects. Correlations between leakage-inducing concentrations of thymol and minimal inhibitory concentrations and minimal bactericidal concentrations suggest that membrane perforation is a principal mode of action of this substance. The thymol-induced decline in intracellular ATP in S. sobrinus appears to be entirely attributable to leakage, whereas in P. gingivalis thymol may also inhibit ATP-generating pathways. Relative changes in the transmembrane potential of resting cells of S. sobrinus pulsed with glucose are as sensitive to thymol as is leakage from this organism. The effects of thymol on transmembrane potential are probably secondary to those arising from leakage of intracellular substances.

References

Jul 1, 1977·Proceedings of the National Academy of Sciences of the United States of America·M D MansonC Van der Drift
Jan 1, 1977·Journal of Supramolecular Structure·S L Barker, E R Kashket
Oct 1, 1979·Journal of Bacteriology·P C Maloney
Aug 1, 1992·Applied and Environmental Microbiology·A Okereke, T J Montville
May 1, 1990·Research in Microbiology·J CorreA Cremieux
May 1, 1990·Research in Microbiology·J J LucchiniA Cremieux
Aug 1, 1986·Infection and Immunity·G R BenderR E Marquis
Jun 1, 1974·Analytical Biochemistry·O H Lowry, J G Carter
Apr 8, 1974·Biochemical and Biophysical Research Communications·P C Laris, H A Pershadsingh
Aug 1, 1994·Oral Microbiology and Immunology·S ShapiroB Guggenheim
Mar 8, 1958·Nature·A H BECKETTA E ROBINSON
May 1, 1962·Analytical Biochemistry·R W ESTABROOK, P K MAITRA

❮ Previous
Next ❯

Citations

May 23, 2001·Archives of Biochemistry and Biophysics·J VillalaínV Micol
Sep 14, 2010·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·A AhmadN Manzoor
Jul 21, 2004·Colloids and Surfaces. B, Biointerfaces·Mariela E SánchezMaría A Perillo
Dec 4, 2013·Comptes rendus biologies·Sameh E HassanienAhmed Bahieldin
Mar 23, 2004·European Journal of Pharmacology·János MagyarPéter P Nánási
Dec 9, 2003·Life Sciences·Norbert SzentandrássyIstván Jóna
Mar 22, 2003·Journal of Ethnopharmacology·K M ParkJ K Hwang
May 16, 2002·British Journal of Pharmacology·János MagyarPéter P Nánási
Oct 24, 2007·Microbial Drug Resistance : MDR : Mechanisms, Epidemiology, and Disease·Roni Shapira, Efrat Mimran
Oct 1, 1996·Oral Microbiology and Immunology·S Shapiro
Mar 29, 2005·Antimicrobial Agents and Chemotherapy·Sara RobledoIván Vélez
Mar 2, 2011·Canadian Journal of Microbiology·Phuong T M Nguyen, Robert E Marquis
Jul 17, 2003·BMC Pharmacology·Norbert SzentandrássyLászló Csernoch
Apr 13, 2011·Experimental & Molecular Medicine·Wanyeon KimBuHyun Youn
Jun 27, 2014·European Journal of Dentistry·Nilima ThosarMonali Rajurkar
Dec 3, 2014·Phytomedicine : International Journal of Phytotherapy and Phytopharmacology·Haq Nawaz BhattiMuhammad Iqbal Choudhary
Jan 25, 2014·Clinical Oral Investigations·Eleonora CiandriniWally Baffone
Sep 18, 2013·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Daniele F O RochaAnita J Marsaioli
Jul 27, 2004·Journal of Herbal Pharmacotherapy·Ethan BaschDavid Sollars
Nov 1, 2012·European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences·Aijaz AhmadNikhat Manzoor
Mar 11, 2008·International Journal of Antimicrobial Agents·Pier Carlo BragaMonica Dal Sasso
Apr 3, 2008·Pest Management Science·Dingfei Hu, Joel Coats
Dec 3, 2014·Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology·Alejandra MartínezAlfonso Catalán
Jul 23, 2003·International Journal of Hygiene and Environmental Health·Nikolaus ThuilleMarkus Nagl
Feb 4, 2014·The Journal of Allergy and Clinical Immunology·Joshua B WechslerPaul J Bryce
Apr 5, 2001·Biochimica Et Biophysica Acta·V MicolJ Villalaín
Nov 2, 2013·Toxicology Mechanisms and Methods·Mohammad Rafiul HaqueMohammed Afroz Ahmad
Feb 16, 2012·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Kim-Chung T PhiHae-Dong Jang
Sep 13, 2011·Journal of Dentistry·A ItthagarunR G Nair
Jun 7, 2011·Chemico-biological Interactions·Dipanwita Dutta DebTapan Chakraborty
Apr 12, 2017·Journal of Evidence-based Complementary & Alternative Medicine·Mohammadmehdi Fani, Jamshid Kohanteb
Oct 3, 2008·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Nisha MathewKalyanasundaram Muthuswamy
May 23, 2018·Phytotherapy Research : PTR·Bahare SalehiJavad Sharifi-Rad
Dec 18, 2009·Biological Reviews of the Cambridge Philosophical Society·Richard M K Saunders
May 30, 2014·Death Studies·Jason Michael Troyer
Mar 5, 2016·The American Journal of Hospice & Palliative Care·Madelaine Lawrence

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.