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The actions of flupenthixol upon 5-hydroxytryptamine-induced aggregation and the uptake of 5-hydroxytryptamine and dopamine by human blood platelets

British Journal of Pharmacology

Dec 1, 1975

D J BoullinM W Orr

PMID: 2360

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Abstract

The effects of the alpha- and beta-isomers of flupenthixol on 5-hydroxytryptamine (5-HT)-induced platelet aggregation and on 5-HT and dopamine uptake were investigated. Alpha-Flupenthixol was 185 times more potent than the beta-isomer as an inhibitor of platelet aggregation. In contrast...read more

Mentioned in this Paper

Flupenthixol
Hydroxytryptamine
Aggregation
Serotonin
Uptake
Intropin
Dopamine Uptake
Thioxanthenes
Dopamine Measurement
Blood Platelets
Paper Details
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    • References4
    • Citations7
  • The actions of flupenthixol upon 5-hydroxytryptamine-induced aggregation and the uptake of 5-hydroxytryptamine and dopamine by human blood platelets

    British Journal of Pharmacology

    Dec 1, 1975

    D J BoullinM W Orr

    PMID: 2360

    DOI:

    Abstract

    The effects of the alpha- and beta-isomers of flupenthixol on 5-hydroxytryptamine (5-HT)-induced platelet aggregation and on 5-HT and dopamine uptake were investigated. Alpha-Flupenthixol was 185 times more potent than the beta-isomer as an inhibitor of platelet aggregation. In contrast...read more

    Mentioned in this Paper

    Flupenthixol
    Hydroxytryptamine
    Aggregation
    Serotonin
    Uptake

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    • Citations7
    • References4
    • Citations7
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