The Activation of the Mirror Neuron System during Action Observation and Action Execution with Mirror Visual Feedback in Stroke: A Systematic Review

Neural Plasticity
Jack J Q ZhangKaren P Y Liu

Abstract

To evaluate the concurrent and training effects of action observation (AO) and action execution with mirror visual feedback (MVF) on the activation of the mirror neuron system (MNS) and its relationship with the activation of the motor cortex in stroke individuals. A literature search using CINAHL, PubMed, PsycINFO, Medline, Web of Science, and SCOPUS to find relevant studies was performed. A total of 19 articles were included. Two functional magnetic resonance imaging (fMRI) studies reported that MVF could activate the ipsilesional primary motor cortex as well as the MNS in stroke individuals, whereas two other fMRI studies found that the MNS was not activated by MVF in stroke individuals. Two clinical trials reported that long-term action execution with MVF induced a shift of activation toward the ipsilesional hemisphere. Five fMRI studies showed that AO activated the MNS, of which, three found the activation of movement-related areas. Five electroencephalography (EEG) studies demonstrated that AO or MVF enhanced mu suppression over the sensorimotor cortex. MVF may contribute to stroke recovery by revising the interhemispheric imbalance caused by stroke due to the activation of the MNS. AO may also promote motor relearning in...Continue Reading

References

Jun 1, 1995·Journal of Neurophysiology·L FadigaG Rizzolatti
Nov 1, 1994·Stroke; a Journal of Cerebral Circulation·S GiaquintoG Nolfe
Jun 22, 1999·Lancet·E L AltschulerV S Ramachandran
Oct 3, 2001·Neuron·G Rizzolatti, G Luppino
Jun 26, 2004·Annual Review of Neuroscience·Giacomo Rizzolatti, Laila Craighero
Apr 22, 2005·The New England Journal of Medicine·Bruce H Dobkin
Apr 30, 2005·Science·Leonardo FogassiGiacomo Rizzolatti
Sep 6, 2005·Clinical Medicine : Journal of the Royal College of Physicians of London·V S Ramachandran
Oct 31, 2006·Progress in Brain Research·Christa NeuperGert Pfurtscheller
Aug 10, 2007·Medical & Biological Engineering & Computing·Kynan EngDaniel Kiper
Aug 16, 2008·Medical Hypotheses·Ti-Fei Yuan, Robert Hoff
Oct 1, 2008·Psychophysiology·Suresh D Muthukumaraswamy, Krish D Singh
Jun 10, 2009·Brain : a Journal of Neurology·V S Ramachandran, Eric L Altschuler
Jun 18, 2009·Neurorehabilitation and Neural Repair·Dennis A NowakGereon R Fink
Jan 9, 2010·NeuroImage·Svenja CaspersSimon B Eickhoff
Mar 9, 2010·Neurorehabilitation and Neural Repair·Kathleen A GarrisonLisa Aziz-Zadeh
Mar 11, 2010·Nature Reviews. Neuroscience·Giacomo Rizzolatti, Corrado Sinigaglia
Apr 20, 2010·The New England Journal of Medicine·Albert C LoPeter Peduzzi
Sep 24, 2010·Journal of Neurology, Neurosurgery, and Psychiatry·Marian E MichielsenRuud W Selles
Nov 6, 2010·Neurorehabilitation and Neural Repair·Marian E MichielsenJohannes B J Bussmann
Jan 17, 2012·Neurorehabilitation and Neural Repair·Farsin HamzeiCornelius Weiller
Oct 6, 2012·Journal of Neuroengineering and Rehabilitation·Youn Joo KangEun Sook Park
Jun 8, 2013·Stroke; a Journal of Cerebral Circulation·Kathleen Alice GarrisonCarolee Joyce Winstein
Nov 13, 2013·Nature Reviews. Neurology·Steven L SmallAna Solodkin
Mar 22, 2014·Journal of Physical Therapy Science·Junghee KimEsther Son
Aug 28, 2014·Neurorehabilitation and Neural Repair·Frederik J A DeconinckGeert J P Savelsbergh
Oct 6, 2014·Annals of Physical and Rehabilitation Medicine·P MarqueI Loubinoux
Oct 19, 2014·Neurorehabilitation and Neural Repair·Holly E RossiterNick S Ward
Mar 17, 2015·Lancet Neurology·Gert KwakkelSteven L Wolf
Apr 4, 2015·Restorative Neurology and Neuroscience·Christian DettmersMircea Ariel Schoenfeld
May 1, 2015·The Cochrane Database of Systematic Reviews·Kate E LaverMaria Crotty

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Citations

Dec 12, 2019·Occupational Therapy International·Yi-Chun LiYa-Yun Lee
Sep 26, 2020·Frontiers in Neuroscience·Martí de Castro-CrosDani Tost
Aug 20, 2019·Restorative Neurology and Neuroscience·Jack Jiaqi Zhang, Kenneth N K Fong
Sep 25, 2021·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·Yuqian ZhangYulong Bai
Oct 31, 2020·Computers in Biology and Medicine·Jin Woo ChoiSungho Jo

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