The active magnetic resonance imaging stent (AMRIS): initial experimental in vivo results with locally amplified MR angiography and flow measurements

Investigative Radiology
Dietmar KivelitzBernd Hamm

Abstract

Magnetic resonance (MR) is limited by artifacts in vessels after stenting. An active MR imaging stent (AMRIS) allows for artifact-free imaging with local improvement in signal-to-noise ratio (SNR). In a rabbit model, we evaluated the imaging properties by MR angiography (MRA) and flow measurements. The AMRIS was placed in the abdominal aorta of five rabbits. At 1.5 T, MRA (three-dimensional fast low-angle shot) was performed before and after intravenous injection of an iron oxide-based, blood-pool contrast medium (dose, 50 micromol Fe/kg), and flow measurements were performed (electrocardiographically triggered phase-contrast cine gradient-echo sequence). Mean SNRs were calculated and flow volume curves were generated. The SNR was 6.0 +/- 0.6 (outside the stent) versus 12.3 +/- 1.1 (inside the stent, P < 0.05) for plain MRA, 21.2 +/- 0.6 versus 40.6 +/- 5.2 (P < 0.05) for contrast-enhanced MRA, and 5.4 +/- 0.4 versus 13.7 +/- 2.1 (P < 0.05) for the magnitude images of flow measurements. Flow volume curves within and distal to the stent were comparable. By using the AMRIS as a vascular stent, the stented vessel segment can be examined with enhanced signal intensity on MRI.

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Citations

Dec 31, 2008·Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance·Kanishka RatnayakaRobert J Lederman
Nov 17, 2010·Radiology·Nils A KraemerElmar Spuentrup
Sep 9, 2005·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Martin BuschDietrich Grönemeyer
Nov 24, 2004·Journal of Magnetic Resonance Imaging : JMRI·David W TrostThomas A Sos
Dec 22, 2004·Journal of Magnetic Resonance Imaging : JMRI·Edward G WalshAndreas S Anayiotos

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