The activity of serum ribonuclease in protein-energy malnutrition

Transactions of the Royal Society of Tropical Medicine and Hygiene
S M el-SewedyA M Zaki


Serum alkaline ribonuclease activity and serum albumin concentration were determined in 25 normal children and 59 children with protein-energy malnutrition. The increase in serum ribonuclease was marked in marasmus and marasmic kwashiorkor. The ribonuclease activity dropped significantly after two weeks of treatment and returned to normal by four weeks. In kwashiorkor, serum ribonuclease activity was significantly lower than control and returned to normal after four weeks of treatment. These findings support previous observations that the serum ribonuclease is a good criterion of the nutritional status and indicates that the enzyme activity, particularly when related to serum albumin, is a good prognostic index in this respect.


Nov 14, 1970·Lancet·A C Walker
Apr 1, 1970·Archives of Disease in Childhood·C E Watson, C Freesemann
Aug 1, 1973·The American Journal of Clinical Nutrition·D M SigulemM Winick
Sep 1, 1972·The American Journal of Nursing·J M Johnson
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Feb 1, 1962·Proceedings of the Society for Experimental Biology and Medicine·N COHENF HOLLANDER
Jul 1, 1962·The Journal of Clinical Investigation·M A ROTHSCHILDS S SCHREIBER


Jan 1, 1978·Transactions of the Royal Society of Tropical Medicine and Hygiene·M M ZeitounS M el-Sewedy

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Alkaline Ribonuclease
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