PMID: 2103157Jan 1, 1990Paper

The actual and potential supply of organ donors in the United States

Clinical Transplants
R W Evans

Abstract

For the past 4 years (1986 to 1989), there has been virtually no change in the number of organ donors, despite significant efforts targeted toward increasing supply. The number of donors has plateaued at about 4,000 annually. Meanwhile, the number of people awaiting transplants continues to increase at a remarkable rate. Between December 1987 and December 1990, the number of people awaiting a kidney, heart, liver, heart-lung or pancreas transplant increased by 65%. This demand/supply disparity has led to much interest in the assessment of the organ procurement system. Such an assessment must endeavor to compare the supply of potential donors with actual donor procurements. Numerous studies have been conducted to estimate potential donor supply. Some relied upon the review of in-hospital death records, whereas others attempted to search and identify potential donors in large mortality databases. Regardless of their source, patient records are examined and databases searched to exclude those deaths where contraindications to organ donation are present. Due to the severe shortage of donors, exclusion criteria have been relaxed to include deaths of marginal potential donors. Six major studies, all conducted between 1975 and 1991, i...Continue Reading

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

© 2021 Meta ULC. All rights reserved