PMID: 9549739Apr 29, 1998Paper

The advantages of intrathecal opioids for spinal fusion in children

Paediatric Anaesthesia
M Goodarzi

Abstract

Two groups of 40 homogeneous patients (ASA physical status (1-2)) with idiopathic scoliosis undergoing spinal fusion with CD instrumentation were studied prospectively. Group A (intrathecal) received a mixture of morphine and sufentanil administered intrathecally at the level of L3-L4 after the induction of anaesthesia. Group B (control) had inhalation and intravenous narcotic anaesthesia. The use of intrathecal opioids resulted in a significant reduction of blood pressure without the use of any hypotensive agents and produced prolonged postoperative analgesia. There was no adverse effect on somatosensory evoked potentials. The dose requirement for the anaesthetic agents was significantly reduced and the blood loss was 27% of their blood volume compared with 53% in the control group. No long or short term impairment of cerebral or spinal function was observed. The use of intrathecal opioids supplemented with other anaesthetic agents is an alternative method with multiple benefits for any major surgery such as spinal fusion.

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Citations

Feb 29, 2008·British Journal of Anaesthesia·S EschertzhuberP Innerhofer
Oct 28, 2011·Regional Anesthesia and Pain Medicine·Sonal SharmaMarcel E Durieux
Jan 8, 2013·World Journal of Orthopedics·Ottokar StundnerStavros G Memtsoudis
Jul 10, 2004·Acta Anaesthesiologica Scandinavica·P K SuominenR L Eyres
Jun 29, 2007·Paediatric Anaesthesia·Tina Hoff Duedahl, Ebba Holme Hansen
May 28, 2008·Paediatric Anaesthesia·Richard HowardUNKNOWN Association of Paediatric Anaesthetists of Great Britain and Ireland
Mar 26, 2004·Anesthesia and Analgesia·Joseph D Tobias
Jan 24, 2007·Anesthesia and Analgesia·Arjunan GaneshGiovanni Cucchiaro
May 7, 2008·Current Opinion in Anaesthesiology·Alain Borgeat, Stephan Blumenthal
Feb 23, 2019·Clinical Spine Surgery : a Spine Publication·Arif MusaGligor Gucev
Jul 22, 2011·The Journal of Bone and Joint Surgery. American Volume·Eva Y W TseKeith D K Luk
Sep 12, 2020·Pain Medicine : the Official Journal of the American Academy of Pain Medicine·Khaled Mohamed FaresAmira Mahmoud Mohamed Osman
Apr 22, 2020·Global Spine Journal·Sagar A ShahMichael J Heffernan
Oct 24, 2020·Paediatric Drugs·Christopher S LeeVidya Chidambaran

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