PMID: 26351505Sep 10, 2015Paper

The Adverse Effects of Pregnancies Complicated by Hemoglobin H (HBH) Disease

Iranian Journal of Pathology
Maryam RabieeNafiseh Zafargandie

Abstract

Hemoglobin (Hb) H disease is a moderate form of α- thalassemia resulting from various genetic defects. HbH disease is not necessarily a benign disorder as has been generally thought. We present hereby a 25- year-old Iranian pregnant woman whom referred to our hospital for blood transfusion. She exhibited the clinical and hematological manifestation of HbH disease. Her father carries a common α-thalassemia deletion while her mother was normal in the hematological profile. The object of this report was to provide information about pregnancies affected by HbH disease.

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