PMID: 11915920Mar 28, 2002Paper

The aging cardiovascular system: changes in autonomic function at rest and in response to exercise

International Journal of Sport Nutrition and Exercise Metabolism
Douglas R SealsP P Jones

Abstract

Tonic vagal modulation of cardiac period (R-R interval) decreases with advancing age, but is greater in middle-aged and older adults who habitually perform aerobic exercise compared with their sedentary peers. Cardiovagal baroreflex sensitivity also declines markedly with age in sedentary adults but only 50% as much in regularly exercising adults. In previously sedentary middle-aged and older adults, a 3-month program of moderate aerobic exercise increases cardiovagal baroreflex sensitivity by 25%. Tonic (basal) sympathetic nervous system (SNS) activity increases with advancing age in both sedentary and habitually exercising adults. Despite this, SNS beta-adrenergic support of energy metabolism (resting metabolic rate--RMR) declines with age in sedentary individuals. However, SNS beta-adrenergic support of RMR is maintained with age in endurance exercise-trained adults and therefore is much greater in middle-aged and older individuals who exercise regularly compared with their sedentary peers. Thus, regular aerobic (endurance) exercise modulates selective age-associated impairments in autonomic nervous system-physiological function.

Citations

Mar 14, 2013·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Arnold F JacobsonErnest V Garcia
Jan 20, 2017·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Hirofumi TanakaDouglas R Seals
Jul 4, 2018·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Alexander J RosenbergTracy Baynard
Oct 10, 2007·BJU International·Karl-Erik Andersson, Brian Olshansky
Dec 17, 2008·Family & Community Health·Hirofumi Tanaka
Oct 8, 2014·Nature Reviews. Nephrology·Jeroen P KoomanPeter Stenvinkel
Jul 10, 2010·Clinical Journal of the American Society of Nephrology : CJASN·Christopher T ChanUNKNOWN Frequent Hemodialysis Network Daily Trial Group
Jul 24, 2020·International Journal of Environmental Research and Public Health·Soo Hwan ByunSeok Jin Hong
Apr 21, 2006·Age and Ageing·Joseph F AudetteWalter R Frontera
Jan 28, 2014·Annals of Noninvasive Electrocardiology : the Official Journal of the International Society for Holter and Noninvasive Electrocardiology, Inc·Matthew J DewhurstPhilip Langley

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