The AIDS epidemic among Spanish drug users: a birth cohort-associated phenomenon

American Journal of Public Health
Jesús CastillaG López-Abente

Abstract

In Spain the number of new acquired immunodeficiency syndrome (AIDS) cases among injection drug users continues to rise. The time trend up to 1994 has been analyzed, with special attention paid to the different generations. The source for injection drug use-related cases was the Spanish AIDS Register. Independent analyses of annual specific rates were run for each sex with the use of an age-period-cohort log-linear model. After adjustment for age and year of diagnosis, AIDS incidence related to injection drug use is associated with specific birth cohorts. Rising values are observed in the successive generations born during the 1950s, peaking in men born in 1962 and women born in 1964. In subsequent cohorts, there is a marked falloff in incidence for both sexes, but this decline is seen to halt in men from the 1972 birth cohort onwards. The overall period effect is upward, yet the trend flattens in the last years. There is a pronounced age effect with maximum values in men and women at ages 29 and 27, respectively. It is essential to urge avoidance of risk behaviors in new generations.

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Citations

May 7, 2010·Annals of Oncology : Official Journal of the European Society for Medical Oncology·R Marcos-GrageraUNKNOWN Non-Hodgkin's Lymphoma Working Group
Jul 31, 2014·International Journal of Environmental Research and Public Health·Paulo Cavalcante Apratto JuniorNádia Cristina Pinheiro Rodrigues
Apr 3, 2016·International Journal for Equity in Health·Zhi LiXinguang Chen
Jan 24, 2017·Enfermedades infecciosas y microbiología clínica·Aitziber AguinagaJesús Castilla
Dec 5, 2018·PloS One·Regina JuanbeltzUNKNOWN EIPT-VHC Study Group
Jun 10, 2020·Revista Española De Enfermedades Digestivas : Organo Oficial De La Sociedad Española De Patología Digestiva·Cristina BurguiJesús Castilla

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