The allergy epidemic extends beyond the past few decades

Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology
Erika IsolauriO Impivaara

Abstract

Increased prevalence of allergic diseases in western societies has been described as an epidemic. The precise turning point for the epidemic and the antigens responsible for it remain obscure. To evaluate how the prevalence of atopic disease has changed in terms of detectable sensitization to aeroallergens and dietary allergens in a cross-sectional comparison of subjects from birth cohorts more than 60 years apart. We studied four groups of 100 subjects each (at ages 7, 27, 47 and 67 years), representing those born in 1990, 1963-66, 1943-46 and in 1923-26, respectively. Serum total and specific IgE concentrations against aeroallergens and dietary allergens were determined. A questionnaire elicited information on symptoms, allergic diseases and medication. The proportion of subjects with detectable IgE antibodies against aeroallergens increased consistently from the oldest to the youngest birth cohorts; chi2 trend=56.809, P<0.0001. Similar progression was not seen in sensitization to dietary allergens. The proportion of those with diagnosed asthma differed significantly (chi2=13.45, P=0.004) across the birth cohorts. The lowest prevalence of asthma and sensitization to dietary allergens was detected in those born in 1943-46, i.e...Continue Reading

References

Nov 18, 1989·BMJ : British Medical Journal·D P Strachan
Oct 1, 1989·Archives of Disease in Childhood·M L BurrE Vaughan-Williams
Jan 1, 1987·The Journal of Allergy and Clinical Immunology·R A BarbeeB Burrows
Apr 1, 1984·Journal of the American Geriatrics Society·J S ThompsonN Tietz
Jan 8, 1994·Lancet·T NakagomiO Nakagomi
May 1, 1996·The Journal of Allergy and Clinical Immunology·T NakagawaY Mizushima
Jun 1, 1996·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·H E Wichmann
Jul 31, 1997·Nature·S E MooreA M Prentice
Jan 7, 1998·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·A YabuharaP G Holt
Jun 8, 2001·The American Journal of Clinical Nutrition·E Isolauri
Jul 12, 2001·The Journal of Allergy and Clinical Immunology·G KannyF Thevenin
Apr 20, 2002·Science·Maria YazdanbakhshRonald van Ree
Jun 14, 2002·The Journal of Allergy and Clinical Immunology·Emma BroadfieldJohn Britton
Sep 21, 2002·Lancet·Tyra KrauseMads Melbye
Mar 19, 2003·The Journal of Allergy and Clinical Immunology·Andrew H Liu, James R Murphy
Jun 6, 2003·The Journal of Allergy and Clinical Immunology·Takushi ShiraiToshinori Nakayama

❮ Previous
Next ❯

Citations

May 20, 2005·Journal of Molecular Medicine : Official Organ of the Gesellschaft Deutscher Naturforscher Und Ärzte·Sabine Hoffjan, Jörg T Epplen
Jun 16, 2010·World Journal of Pediatrics : WJP·Zorica ZivkovićOmer Adžović
Oct 31, 2006·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Ilaria BaiardiniGiorgio Walter Canonica
Aug 10, 2006·Medical Anthropology·Betsy Pohlman, Gay Becker
Aug 18, 2012·Anthropology & Medicine·Roberta Raffaetà
May 27, 2006·Current Opinion in Otolaryngology & Head and Neck Surgery·Xiu-Min Li, Kamal Srivastava
Nov 6, 2007·Applied and Environmental Microbiology·Noah FiererMark T Hernandez
Oct 4, 2006·International Archives of Allergy and Immunology·R RonchettiM P Villa
Dec 15, 2007·Allergy, Asthma, and Clinical Immunology : Official Journal of the Canadian Society of Allergy and Clinical Immunology·Kerstin GerholdEckard Hamelmann
Sep 17, 2010·Allergy, Asthma, and Clinical Immunology : Official Journal of the Canadian Society of Allergy and Clinical Immunology·Jason Behrmann
Sep 16, 2011·Italian Journal of Pediatrics·PeiFen LiaoHaiLun Sun
Nov 1, 2012·Clinical and Translational Allergy·Moises A CalderonNikolaos Papadopoulos
Aug 5, 2005·Environmental Health Perspectives·Paul John Beggs, Hilary Jane Bambrick
Mar 26, 2008·Twin Research and Human Genetics : the Official Journal of the International Society for Twin Studies·Corrado FagnaniMaria Antonietta Stazi
Jan 12, 2008·World Journal of Gastroenterology : WJG·Natasha-A KoloskiGraham Radford-Smith
Aug 21, 2009·World Journal of Pediatrics : WJP·Dirk Van GyselFrans De Baets
Dec 7, 2013·The Journal of Asthma : Official Journal of the Association for the Care of Asthma·Ning SongXixin Yan
Aug 1, 2005·Expert Review of Pharmacoeconomics & Outcomes Research·Ilaria BaiardiniGiorgio Walter Canonica
Feb 4, 2009·Chest·Hirofumi MatsuokaMichiaki Mishima
Aug 30, 2012·Clinics in Chest Medicine·Nour Baïz, Isabella Annesi-Maesano
May 18, 2012·Biosensors & Bioelectronics·Rouslan V OlkhovAndrew M Shaw
Oct 22, 2008·International Journal for Parasitology·Angelika WagnerUrsula Wiedermann
Jul 14, 2007·The Journal of Allergy and Clinical Immunology·Roberto J RonaCharlotte Madsen
May 2, 2009·International Journal of Cancer. Journal International Du Cancer·Joseph L WiemelsMargaret Wrensch
Jan 30, 2009·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·Elke GovaereFrans De Baets
Aug 20, 2008·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·Sonia BrescianiniBianca Barletta
Dec 15, 2007·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·Elke GovaereFrans De Baets
Apr 25, 2006·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·S F BloomfieldJ Pickup
Oct 12, 2007·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·J MacanB Kanceljak-Macan
Jul 19, 2006·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·Francesco CataldoUNKNOWN SIGENP and GLNBI Working Groups on Food Intolerances
Feb 14, 2008·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·P M MatricardiS Lau
Sep 28, 2006·Allergy·I BaiardiniG W Canonica
Aug 13, 2010·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·R-F ChenK D Yang
Jan 25, 2011·Allergy·Tiina LaatikainenT Haahtela
May 13, 2014·Allergy·B I NwaruUNKNOWN EAACI Food Allergy and Anaphylaxis Guidelines Group
Nov 12, 2013·Allergy·B I NwaruUNKNOWN EAACI Food Allergy and Anaphylaxis Guidelines Group
Dec 8, 2010·The Journal of Allergy and Clinical Immunology·Alessandro FiocchiRichard F Lockey
Dec 8, 2009·The Korean Journal of Parasitology·Cihangir Akdemir, Erdogan Soyucen

❮ Previous
Next ❯

Related Concepts

Related Feeds

Atopic Dermatitis

Atopic dermatitis is a chronic inflammatory genetically determined disease of the skin marked by increased ability to form reagin (IgE), with increased susceptibility to allergic rhinitis and asthma, and hereditary disposition to a lowered threshold for pruritus. Discover the latest research on atopic dermatitis here.

Asthma

This feed focuses in Asthma in which your airways narrow and swell. This can make breathing difficult and trigger coughing, wheezing and shortness of breath.

Allergy and Asthma

Allergy and asthma are inflammatory disorders that are triggered by the activation of an allergen-specific regulatory t cell. These t cells become activated when allergens are recognized by allergen-presenting cells. Here is the latest research on allergy and asthma.

Allergies & Environmental Factors

Environmental factors are strongly associated with the prevalence of allergies and are an increasing health concern worldwide. Discover the latest research on Allergies and Environmental Factors here.

Related Papers

Annual Review of Public Health
Diane R Gold, Rosalind Wright
Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology
American College of Allergy, Asthma, & Immunology
Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology
A Høst
Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology
Francesco CataldoSIGENP and GLNBI Working Groups on Food Intolerances
© 2022 Meta ULC. All rights reserved