The alpha2 Gene alleles of the platelet collagen receptor integrin alpha2 beta1 in Turkish children with cerebral infarct

Thrombosis Research
N AkarT Sipahi

Abstract

The possible role of point mutations in the platelet integrin alpha2 beta1 gene in Turkish children with ischemic stroke was evaluated in this study. The case-control study included 44 pediatric patients with cerebral infarct (age range, 10 months to 18 years) and 96 healthy unrelated individuals. Genotyping was performed according to previously described methods. Distribution of the three haplotypes were 36.4%, 45.3%, 10.4% and 31.8%, 50.0%, 13.6% for the controls and the patients, respectively. A new fourth haplotype was found which was 7.8% and 4.5% respectively. Our data indicated that these haplotypes are not risk factors in pediatric stroke group.

References

Jul 1, 1993·Journal of Child Neurology·A R Riela, E S Roach
Oct 1, 1996·Blood Coagulation & Fibrinolysis : an International Journal in Haemostasis and Thrombosis·U Nowak-GöttlH Vielhaber
Oct 15, 1998·Journal of Neurology, Neurosurgery, and Psychiatry·V GanesanF J Kirkham
Nov 10, 2001·Hematology·James B. BusselAlan D. Michelson

❮ Previous
Next ❯

Citations

Nov 25, 2003·Current Opinion in Pediatrics·Fenella J Kirkham
Jun 2, 2011·International Journal of Alzheimer's Disease·Marjelo A MinesRichard S Jope
Nov 18, 2004·Journal of the Neurological Sciences·Chih-Hung ChenUNKNOWN Southern Taiwan Young Stroke Study Group
Jan 9, 2014·The International Journal of Neuroscience·Guangliang WuLian Gu
Dec 7, 2002·Stroke; a Journal of Cerebral Circulation·James F Meschia
Jan 25, 2003·Blood Coagulation & Fibrinolysis : an International Journal in Haemostasis and Thrombosis·Abdullah MaakarounYves Gruel
Jul 6, 2006·Thrombosis Research·Georgios K NikolopoulosGeorgios Vaiopoulos

❮ Previous
Next ❯

Related Concepts

Related Feeds

Adhesion Molecules in Health and Disease

Cell adhesion molecules are a subset of cell adhesion proteins located on the cell surface involved in binding with other cells or with the extracellular matrix in the process called cell adhesion. In essence, cell adhesion molecules help cells stick to each other and to their surroundings. Cell adhesion is a crucial component in maintaining tissue structure and function. Discover the latest research on adhesion molecule and their role in health and disease here.

Brain Ischemia

Brain ischemia is a condition in which there is insufficient blood flow to the brain to meet metabolic demand. Discover the latest research on brain ischemia here.