PMID: 3745277Sep 1, 1986Paper

The alteration of myosin isoform compartmentation in specific mutants of Caenorhabditis elegans

The Journal of Cell Biology
Henry F EpsteinL A Mackinnon

Abstract

Myosin isoforms A and B are located at the surface of the central and polar regions, respectively, of thick filaments in body muscle cells of Caenorhabditis elegans, whereas paramyosin and a distinct core structure comprise the backbones of these filaments. Thick filaments and related structures were isolated from nematode mutants that have altered thick filament protein compositions. These mutant filaments and their complexes with specific antibodies were studied by electron microscopy to determine the distribution of the two myosins. The compartmentation of the two myosin isoforms in body wall muscle thick filaments depends not only upon the intrinsic properties of the myosins but their interactions with other components such as paramyosin and their relative quantities determined by synthesis.

References

Jul 1, 1977·Journal of Molecular Biology·A R MacLeodS Brenner
Mar 1, 1985·The Journal of Cell Biology·H F EpsteinG C Berliner
Mar 1, 1973·Proceedings of the National Academy of Sciences of the United States of America·D C TurnerH M Eppenberger
Dec 5, 1974·Journal of Molecular Biology·R H WaterstonS Brenner
Dec 5, 1974·Journal of Molecular Biology·H F EpsteinS Brenner
Feb 1, 1980·Proceedings of the National Academy of Sciences of the United States of America·J M Zengel, H F Epstein

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Citations

Jan 1, 1993·Developmental Dynamics : an Official Publication of the American Association of Anatomists·C J SutherlandE C Hardeman
Jan 1, 1990·Molecular Neurobiology·H F Epstein
Dec 1, 1992·Developmental Biology·H F Epstein, S I Bernstein
Dec 1, 1992·Developmental Biology·E Bandman
Aug 1, 1989·The Journal of Cell Biology·P Vibert, L Castellani
Oct 1, 1993·The Journal of Cell Biology·P R Deitiker, H F Epstein
Sep 13, 2007·Genome Biology·Rebecca M FoxDavid M Miller
Mar 19, 2003·The Journal of Cell Biology·Hongjun LiuSanford I Bernstein
Jan 1, 1989·Cell Motility and the Cytoskeleton·R H Waterston
Jan 1, 1989·Developmental Genetics·P N AdlerB Brunk
Dec 1, 1988·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·H F Epstein
Mar 1, 2012·Journal of Molecular Biology·Sheetal S SalviUpendra Nongthomba
Jul 1, 2005·Physiological Reviews·Scott L Hooper, Jeffrey B Thuma
Oct 1, 1989·Molecular & General Genetics : MGG·I N MaruyamaS Brenner
Dec 1, 1987·Journal of Muscle Research and Cell Motility·H F EpsteinG C Berliner
Dec 1, 1992·Journal of Muscle Research and Cell Motility·D A Gordon, S Lowey
Oct 3, 2002·Journal of Cell Science·Alex H HutagalungHenry F Epstein
Mar 1, 1991·Science·H F Epstein, D A Fischman

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