PMID: 15333702Aug 31, 2004Paper

The amino acid need for milk synthesis is defined by the maximal uptake of plasma amino acids by porcine mammary glands

The Journal of Nutrition
Xinfu GuanNathalie L Trottier

Abstract

To define dietary indispensable amino acid (IAA) needs for milk synthesis by the mammary glands (MG), 16 lactating sows were fed 1 of 4 isocaloric diets varying in protein concentrations (from 78 to 235 g/kg) with an ideal amino acid (AA) pattern. On d 9, 13, 17, and 21 of lactation, blood samples were obtained simultaneously from a carotid artery and the main mammary vein every 30 min over 6 h. A quadratic regression model of the log mammary arteriovenous difference (AVD) of plasma IAA (ŷ) against daily intake of dietary IAA (X) was established. First, the reverse log intercept, defined as the mammary AVD at zero dietary AA supply, was used to quantify the contribution of endogenous IAA. The quantification was validated by body N balance coupled with AA composition analysis. Then, the estimated vertex (ŷ(max), X(i)) was used in 2 aspects: 1) The maximal mammary uptake of plasma IAA, quantified by multiplying the maximal mammary AVD and plasma flow rate, was considered the physiological IAA need for milk synthesis. 2) Corresponding to the ŷ(max), dietary IAA intake (X(i)) would represent the total dietary IAA requirement, i.e., the sum of maintenance need and milk synthesis need after adjustment for body weight loss. Thus, diet...Continue Reading

References

Jan 1, 1979·The Journal of Dairy Research·E RoetsG Peeters
Dec 1, 1977·Journal of Dairy Science·J E WohltC L Davis
Jul 15, 1977·The Biochemical Journal·V A Mezl, W E Knox
Nov 1, 1991·The British Journal of Nutrition·V E BaracosM Marie
Oct 1, 1987·Journal of Animal Science·W A Lellis, V C Speer
Mar 1, 1980·Journal of Animal Science·D L Rousselow, V C Speer
May 1, 1995·Journal of Animal Science·N L TrottierR A Easter
Aug 1, 1993·Journal of Animal Science·L J JohnstonJ W Rust
Sep 1, 1993·Journal of Animal Science·R H KingW G Brown
Jun 1, 1996·Journal of Animal Science·B T RichertL J Johnston
Jul 1, 1996·Journal of Animal Science·D A KnabeC R Dove
May 1, 1997·Journal of Animal Science·N L TrottierR A Easter
Jul 1, 1997·Journal of Animal Science·B T RichertS Kershaw
Jul 1, 1997·The Proceedings of the Nutrition Society·N L Trottier
May 15, 1998·Journal of Animal Science·K J TouchetteR D Boyd
Jun 11, 1998·Journal of Animal Science·K J TouchetteR D Boyd
Jul 3, 1998·The Journal of Nutrition·S DeSantiagoS M Hutson
Jul 17, 1998·The American Journal of Clinical Nutrition·A SuryawanS M Hutson
Nov 10, 1998·The Biochemical Journal·G Wu, S M Morris
Jul 14, 2000·Physiological Reviews·D B Shennan, M Peaker
Nov 4, 2000·Journal of Animal Science·S C JacksonW L Hurley
Mar 8, 2002·Journal of Animal Science·P R O'QuinnG Wu
Jun 4, 2002·The Journal of Nutrition·Xinfu GuanNathalie L Trottier
Jul 26, 2003·The Biochemical Journal·Russell HydeHarinder S Hundal

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.