The Analgesia Nociception Index: a pilot study to evaluation of a new pain parameter during labor

International Journal of Obstetric Anesthesia
M Le GuenM Fischler

Abstract

Objective pain assessment that is not subject to influences from either cultural or comprehension issues is desirable. Analysis of heart rate variability has been proposed as a potential method. This pilot study aimed to assess the performance of the PhysioDoloris™ analgesia monitor which calculates an Analgesia Nociception Index derived from heart rate variability. It was compared with visual analogical pain scores. Forty-five parturients who requested epidural analgesia were recruited. Simultaneous couplets of pain scores and Analgesia Nociception Index values were recorded every 5 min regardless of the presence or absence of uterine contractions. The relationship between indices was characterized, and a cut-off value of Analgesia Nociception Index corresponding to a visual analogical score >30 (range 0-100) was used to determine the positive and negative predictive value of the Analgesia Nociception Index. There was a negative linear relationship between visual analogical pain scores and Analgesia Nociception Index values regardless of the presence of uterine contractions (regression coefficient ± SEM=-0.18 ± 0.032 for entire dataset). Uterine contraction significantly reduced the Analgesia Nociception Index (P<0.0001). Usin...Continue Reading

References

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Citations

Apr 25, 2013·British Journal of Anaesthesia·T LedowskiN Parker
Mar 17, 2015·Anaesthesia·R CowenC Bantel
Apr 23, 2017·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·Rami IssaPhilippe Richebé
Jun 21, 2017·Journal of Clinical Monitoring and Computing·Nurseda DundarMine Solak
Oct 11, 2017·Journal of Neurosurgical Anesthesiology·Lakshman K KommulaGanne S Umamaheswara Rao
Mar 10, 2020·Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology·Ali JendoubiMohamed Houissa
Nov 17, 2016·Journal of Clinical Monitoring and Computing·Laura ButruilleRégis Logier
Jan 10, 2020·Journal of Clinical Monitoring and Computing·Maria J SusanoPedro Amorim
Feb 7, 2021·Sensors·Jerry ChenJiann-Shing Shieh
Apr 6, 2021·Journal of Veterinary Research·Ismael Hernández-AvalosCarlos Manuel Acevedo-Arcique
Aug 7, 2019·Journal of Gynecology Obstetrics and Human Reproduction·Clémence VamourThameur Rakza

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