The Analgesic, Anti-Inflammatory and Anti-Pyretic Activities of Tinospora cordifolia

Advances in Clinical and Experimental Medicine : Official Organ Wroclaw Medical University
Liaqat HussainMuhammad Ibrahim

Abstract

Tinospora cordifolia (T. cordifolia) is a valuable resource due to its traditional uses in the treatment of pain, fever and inflammation, but no sufficient scientific literature is available online to confirm its traditional uses in these ailments. This study was carried out to validate the traditional uses of T. cordifolia in treating pain, inflammation and pyrexia, using albino mice as an experimental animal model. The analgesic effects of T. cordifolia extract were assessed by using the acetic acid-induced writhing test, hot plate test and tail-flick test. The carrageenan test was performed to assess anti-inflammatory potential, and anti-pyretic activity was evaluated by the brewer's yeast-induced pyrexia method. The results showed that the T. cordifolia extract exhibited significant analgesic effects in a dose-dependent manner in the three pain models tested. The extract also exhibited significant anti-inflammatory effects in the carrageenan-induced inflammation test and antipyretic effects in the brewer's yeast-induced pyrexia test in dose-dependent manner compared to the effects observed in the control group animals. From the findings of the present study, it can be concluded that T. cordifolia extract has strong analgesi...Continue Reading

Citations

Jan 11, 2018·Journal of Immunology Research·Sultan Alsuhaibani, Masood A Khan
Sep 24, 2020·Drug Metabolism and Personalized Therapy·Md Anzar AlamMariyam Ahad
Nov 1, 2020·Drug Metabolism and Personalized Therapy·Sana FatimaUNKNOWN Murtada Taha
Feb 6, 2021·Journal of Complementary & Integrative Medicine·Md Anzar AlamBangalore Nagaraj Renuka
Jun 22, 2021·Journal of Ayurveda and Integrative Medicine·Meenakshi PandeySujata Kadam

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