The anatomical and computational basis of the rat head-direction cell signal

Trends in Neurosciences
Patricia E SharpJ Cho

Abstract

As a rat navigates through space, neurons called head-direction (HD) cells provide a signal of the rat's momentary directional heading. Although partly guided by landmarks, the cells also show a remarkable ability to track directional heading based on angular head movement. Theoretical models suggest that the HD cells are linked together to form an attractor network, and that cells which signal angular velocity update the directional setting of the attractor. Recently, cell types similar to those required theoretically have been discovered in the lateral mammillary and dorsal tegmental nuclei. Lesion and anatomical data suggest these nuclei might constitute the postulated attractor-path integration mechanism, and that they provide the HD cell signal to cortical areas where it has been observed.

References

Sep 17, 1984·Brain Research·R LiuG Wickern
Apr 25, 1995·Proceedings of the National Academy of Sciences of the United States of America·R Ben-YishaiH Sompolinsky
Oct 15, 1996·Proceedings of the National Academy of Sciences of the United States of America·E Salinas, L F Abbott
Jan 1, 1996·Brain Research Bulletin·J S TaubeR W Stackman

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Citations

Nov 8, 2005·Experimental Brain Research·Kathryn J JefferyMichael I Anderson
Mar 21, 2009·Experimental Brain Research·Volker DiekmannWolfgang Becker
May 4, 2011·Neuroradiology·Hyeok Gyu KwonSung Ho Jang
Sep 28, 2004·Journal of Comparative Physiology. A, Neuroethology, Sensory, Neural, and Behavioral Physiology·Gerald E Hough, Verner P Bingman
Dec 5, 2006·Biological cybernetics·Eric L Sauser, Aude G Billard
Sep 1, 2005·Journal of Computational Neuroscience·Eun-Hyoung ParkPaul So
May 1, 2008·Journal of Computational Neuroscience·Minija TamosiunaiteFlorentin Wörgötter
Apr 1, 2010·Journal of Computational Neuroscience·Peter StrattonJanet Wiles
Jan 16, 2003·Physiology & Behavior·J E BrownJ S Taube
Jul 31, 2001·Trends in Neurosciences·X J Wang
Aug 6, 2003·Trends in Neurosciences·Loren M Frank, Emery N Brown
May 25, 2006·Journal of Experimental Psychology. Learning, Memory, and Cognition·M Jeanne ShollKatherine A DellaPorta
Jan 20, 2006·Behavioral Neuroscience·Paul A Dudchenko, Larissa E Zinyuk
Dec 5, 2003·Network : Computation in Neural Systems·Jadin C Jackson, A David Redish
Jun 25, 2004·Network : Computation in Neural Systems·Jonathan Rubin, Amitabha Bose
Jul 8, 2011·Proceedings. Biological Sciences·Midori SakuraHitoshi Aonuma
Jun 3, 2006·Learning & Memory·Anna S Mitchell, John C Dalrymple-Alford
Mar 8, 2007·Annual Review of Neuroscience·Jeffrey S Taube
Nov 2, 2012·Journal of Neurophysiology·Jeffrey S TaubeRussell J Frohardt
Aug 10, 2012·Journal of Neurophysiology·Benjamin J ClarkJeffrey S Taube
Nov 19, 2011·Neural Computation·Sukbin Lim, Mark S Goldman
Sep 6, 2007·PLoS Computational Biology·Mathias FranziusLaurenz Wiskott
Sep 5, 2008·PLoS Computational Biology·Gustavo DecoKarl Friston
Jan 30, 2009·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Ryan M Yoder, Jeffrey S Taube
Jan 16, 2009·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Benjamin J ClarkJeffrey S Taube
Nov 20, 2009·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Gary M MuirJeffrey S Taube
Jan 13, 2006·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·D YoganarasimhaJames J Knierim
Apr 3, 2012·Annual Review of Neuroscience·James J Knierim, Kechen Zhang
Apr 8, 2014·Neuroscience·M E Shinder, J S Taube
Jul 21, 2009·Neurobiology of Learning and Memory·Michael E Hasselmo

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