The anterior heart-forming field: voyage to the arterial pole of the heart

Trends in Genetics : TIG
Robert G Kelly, Margaret E Buckingham

Abstract

Studies of vertebrate heart development have identified key genes and signalling molecules involved in the formation of a myocardial tube from paired heart-forming fields in splanchnic mesoderm. The posterior region of the paired heart-forming fields subsequently contributes myocardial precursor cells to the inflow region or venous pole of the heart. Recently, a population of myocardial precursor cells in chick and mouse embryos has been identified in pharyngeal mesoderm anterior to the early heart tube. This anterior heart-forming field gives rise to myocardium of the outflow region or arterial pole of the heart. The amniote heart is therefore derived from two myocardial precursor cell populations, which appear to be regulated by distinct genetic programmes. Discovery of the anterior heart-forming field has important implications for the interpretation of cardiac defects in mouse mutants and for the study of human congenital heart disease.

References

Jan 1, 1973·Journal of Ultrastructure Research·S Virágh, C E Challice
Aug 1, 1995·Circulation Research·M L Kirby, K L Waldo
Sep 1, 1997·Trends in Genetics : TIG·A B Firulli, E N Olson
Nov 5, 1997·Cell·M C Fishman, E N Olson
Feb 17, 1998·Cardiovascular Research·S J ConwayA J Copp
Jan 23, 1999·Nature Genetics·K SekineS Kato
Feb 13, 1999·Cell·B L Hogan
Apr 6, 1999·Trends in Cardiovascular Medicine·R G KellyM E Buckingham
Jun 8, 1999·The Journal of Clinical Investigation·K WaldoM L Kirby
Jun 22, 1999·Developmental Biology·B G BruneauC E Seidman
Apr 15, 2000·Developmental Dynamics : an Official Publication of the American Association of Anatomists·J Lough, Y Sugi
Jul 6, 2000·Trends in Cardiovascular Medicine·M FarrellM L Kirby
Jul 7, 2000·Developmental Biology·V M ChristoffelsA F Moorman
Sep 6, 2000·Trends in Genetics : TIG·J N Chen, M C Fishman
Sep 23, 2000·Nature·D Srivastava, E N Olson
Nov 4, 2000·Biochemical and Biophysical Research Communications·H OhuchiN Itoh
Feb 13, 2001·Genes & Development·E Tzahor, A B Lassar
Mar 10, 2001·Nature Genetics·L A Jerome, V E Papaioannou
Jun 20, 2001·The Journal of Clinical Investigation·M J FarrellM L Kirby
Oct 5, 2001·Trends in Genetics : TIG·J A Epstein
Jan 11, 2002·Developmental Biology·C H MjaatvedtR R Markwald

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Citations

Mar 24, 2007·Cellular and Molecular Life Sciences : CMLS·W M H HoogaarsV M Christoffels
Mar 24, 2007·Cellular and Molecular Life Sciences : CMLS·A A FilipczykC L Mummery
May 6, 2009·Pediatric Cardiology·Jason T LamKarl-Ludwig Laugwitz
Dec 8, 2009·Pediatric Cardiology·Ying TianEdward E Morrisey
Jun 26, 2013·Cell and Tissue Research·Monika Zmojdzian, Krzysztof Jagla
Dec 4, 2003·Biochemical and Biophysical Research Communications·Hong ZhangMasatsugu Hori
Nov 5, 2003·Gene·Kathryn L MaschhoffH Scott Baldwin
Jun 20, 2006·International Journal of Cardiology·Massimo BaravelliRoberto Tiraboschi
Jun 1, 2005·Pharmacology & Therapeutics·Hiroshi Akazawa, Issei Komuro
Mar 20, 2004·Trends in Cardiovascular Medicine·Nadira AhmadMichael Rebagliati
May 12, 2005·Trends in Cardiovascular Medicine·Robert G Kelly
Nov 24, 2005·Nature Reviews. Genetics·Margaret BuckinghamStéphane Zaffran
Feb 6, 2008·Proceedings of the National Academy of Sciences of the United States of America·Monika ZmojdzianKrzysztof Jagla
Jul 14, 2007·Antioxidants & Redox Signaling·Steven A Fisher, Warren W Burggren
Mar 24, 2011·Cardiovascular Research·Diego FrancoAmelia Aránega
May 24, 2011·Cardiovascular Research·Jeroen Bakkers
Sep 28, 2002·Current Opinion in Pediatrics·Ellen Dees, H Scott Baldwin
Jul 11, 2007·TheScientificWorldJournal·Paige SniderSimon J Conway
Mar 19, 2008·Genes & Development·Ethan David Cohen, Edward E Morrisey
Apr 26, 2007·Annual Review of Cell and Developmental Biology·Radwan Abu-Issa, Margaret L Kirby
Mar 20, 2012·Circulation Research·Jiandong Liu, Didier Y R Stainier
Feb 22, 2012·Circulation Research·Zhan-Peng HuangDa-Zhi Wang
Feb 3, 2012·European Journal of Histochemistry : EJH·C SerradifalcoV Di Felice
Mar 1, 2008·Regenerative Medicine·Stephen Dalton
May 24, 2007·Proceedings of the National Academy of Sciences of the United States of America·Lizhu LinSylvia M Evans
Oct 2, 2003·Proceedings of the National Academy of Sciences of the United States of America·Martina ZikovaKrzysztof Jagla
Apr 9, 2004·Proceedings of the National Academy of Sciences of the United States of America·Wei LiuJames F Martin
Jun 20, 2012·Differentiation; Research in Biological Diversity·Laura E BriggsAndy Wessels
Apr 23, 2004·The Anatomical Record. Part A, Discoveries in Molecular, Cellular, and Evolutionary Biology·Jörg Männer
Apr 24, 2012·Differentiation; Research in Biological Diversity·Stéphane Zaffran, Robert G Kelly
Sep 15, 2009·Experimental Cell Research·Christine Gonzales, Thierry Pedrazzini

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