The anti-inflammatory action of nepitrin, a flavonoid

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O P Agarwal

Abstract

The anti-inflammatory efficacy of nepitrin (5,3',4'-trihydroxy-6-methoxy flavone), a flavonoid, was investigated in both acute and chronic models of inflammation in rats. Nepitrin was found to possess significant anti-inflammatory activity in the exudative and proliferative phases of inflammation. This action of nepitrin could be due to its anti-bradykinin and anti-angiotensin action. Nepitrin also possessed anti-pyretic and weak analgesic activity. The study reveals that nepitrin may be useful as an anti-inflammatory and anti-arthritic agent.

References

Jun 1, 1971·Japanese Journal of Pharmacology·M B GuptaK P Bhargava
Jan 1, 1981·Toxicon : Official Journal of the International Society on Toxinology·O P Agarwal, A Nagaratnam
Jul 1, 1952·J R Sanit Inst·J L BURN
Jun 1, 1959·The American Journal of Physiology·V MENKIN
Nov 1, 1960·The Journal of Pharmacy and Pharmacology·P F D'ARCYS B TOWNSEND
Feb 1, 1962·British Journal of Pharmacology and Chemotherapy·N K BHIDE
Jul 1, 1962·The Journal of Pharmacy and Pharmacology·J M HARRIS, P S SPENCER
Dec 1, 1962·Proceedings of the Society for Experimental Biology and Medicine·C A WINTERG W NUSS
Aug 1, 1963·British Journal of Pharmacology and Chemotherapy·B B NEWBOULD
May 1, 1963·Journal of Medicinal Chemistry·U M TEOTINOD DELLABELLA
Apr 1, 1962·British Journal of Pharmacology and Chemotherapy·B J NORTHOVER, G SUBRAMANIAN
Mar 1, 1952·British Journal of Pharmacology and Chemotherapy·A SPINKS, J H BURN

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Citations

Apr 28, 2009·European Biophysics Journal : EBJ·Alejandra Ester RotelliLilian Eugenia Pelzer
Apr 1, 1988·Journal of Ethnopharmacology·C M SimõesA Langeloh
Apr 22, 2014·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Yoshiaki AmakuraTakashi Yoshida
Jul 27, 1999·Life Sciences·G Di CarloF Capasso
May 5, 2007·Journal of Ethnopharmacology·D Avila-PeñaH Suárez-Roca
Jul 19, 2012·BioFactors·Ana GomesEduarda Fernandes
Dec 1, 1984·The Journal of Pharmacy and Pharmacology·A VillarM J Alcaraz
Jun 6, 2006·Biochemical Pharmacology·Sanghamitra BandyopadhyayNaibedya Chattopadhyay
Nov 23, 2016·Critical Reviews in Food Science and Nutrition·Samuel D HughesNagaraja Haleagrahara
Jun 18, 2002·The Journal of Pharmacology and Experimental Therapeutics·Jong S KangKyu-Hwan Yang
Oct 10, 2001·FEBS Letters·D A RicuperoR H Goldstein
Feb 19, 2016·Experimental and Therapeutic Medicine·Ling Chen, Wei Zhao
Mar 5, 2021·Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie·Alena LiskovaPeter Kubatka
Jun 20, 2002·Transplantation Proceedings·K MuraokaK Yamamoto
Jul 3, 2021·Pharmaceuticals·Patrícia I C GodinhoVera L M Silva
Jun 5, 2017·Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie·Hasandeep SinghBalbir Singh

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