The antibacterial and anticancer properties of zinc oxide coated iron oxide nanotextured composites

Colloids and Surfaces. B, Biointerfaces
Tushar K JanaKuntal Chatterjee

Abstract

Core-shell α-Fe2O3-ZnO structures of different nanotextured morphology were synthesized through wet chemical routes using different solvents like ethanol, ethanolamine, water and acetaldehyde. Morphological tuning using different solvents resulted in the formation of different shapes, such as disc, spindle, rod and sphere (abbreviated as FZ-ND, FZ-NSP, FZ-NR and FZ-NS, respectively). Structural, morphological and compositional characterization of these nanoparticles (NPs) has been carried out. Antibacterial efficacy of the synthesized NPs was checked against Gram negative V. cholerae N16961 (VcN16961) and Gram positive S. aureus bacteria by recording optical density (OD) at different time points. Among the NPs tested, FZ-NSP was found to be the most effective against VcN16961, while FZ-NR showed maximum efficacy against S. aureus, implying the importance of nanotextured surface as well as the morphology in the manifestation of antibacterial activity. The kinetics of growth for both the bacteria has been modelled using logistic approach. Cytotoxicity was evaluated through MTT (3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyltetrazolium bromide) assay against human breast adenocarcinoma cell line (MCF-7), human hepatocarcinoma cell line...Continue Reading

Citations

Jan 5, 2021·Frontiers in Bioengineering and Biotechnology·Heba Salah AbbasMuddukrishnaiah Kotakonda
Oct 25, 2020·Chemosphere·Rekha PachaiappanMu Naushad
Aug 25, 2020·Industrial & Engineering Chemistry Research·Athanasios MilionisDimos Poulikakos

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