The antibacterial, phytochemicals and antioxidants evaluation of the root extracts of Hydnora africanaThunb. used as antidysenteric in Eastern Cape Province, South Africa

BMC Complementary and Alternative Medicine
O A Wintola, A J Afolayan

Abstract

To determine the anti-dysenteric, phytochemicals and antioxidative properties of the root extracts of Hydnora africana. The use of plants for the treatment of dysentery and other diseases in traditional medicine has increased on the basis of these rich traditional medicine systems. Series of pharmacological tests are recommended since the aetiology of many diseases may be due to more than one factor. The agar well diffusion method was used to determine the susceptibility of bacterial strains to crude extracts of the plant. The minimum inhibitory concentration was determined by the microdilution test. The presence of phytochemicals and antioxidant was also assessed using standard methods. The antimicrobial activity of H. africana against all the tested organisms demonstrated a mean zone diameter of inhibition ranging from 0 to 25 mm. The MIC of the extracts ranged from 0.071 to 5.0 mg/mL. Antioxidant activity showed lower ferric reducing activities, moderate nitric oxide, moderate DPPH and higher ABTS scavenging activities of the plant. Phytochemical assay revealed the presence and equivalent quantity of alkaloids, tannins, flavonoids, saponins and phenolic acid in the extracts. The water and methanol extracts were also shown as...Continue Reading

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Citations

May 3, 2016·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Haidan YuanGuangchun Piao
Jun 2, 2018·Oxidative Medicine and Cellular Longevity·Samara Alves BritoAlmir Gonçalves Wanderley
Jul 28, 2018·Oxidative Medicine and Cellular Longevity·Uilson Pereira Dos SantosEdson Lucas Dos Santos

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