The antibiotic crisis: How bacterial predators can help

Computational and Structural Biotechnology Journal
Juana PérezJosé Muñoz-Dorado

Abstract

Discovery of antimicrobials in the past century represented one of the most important advances in public health. Unfortunately, the massive use of these compounds in medicine and other human activities has promoted the selection of pathogens that are resistant to one or several antibiotics. The current antibiotic crisis is creating an urgent need for research into new biological weapons with the ability to kill these superbugs. Although a proper solution requires this problem to be addressed in a variety of ways, the use of bacterial predators is emerging as an excellent strategy, especially when used as whole cell therapeutic agents, as a source of new antimicrobial agents by awakening silent metabolic pathways in axenic cultures, or as biocontrol agents. Moreover, studies on their prey are uncovering mechanisms of resistance that can be shared by pathogens, representing new targets for novel antimicrobial agents. In this review we discuss potential of the studies on predator-prey interaction to provide alternative solutions to the problem of antibiotic resistance.

References

Aug 1, 1988·The Journal of Antibiotics·H IrschikH Reichenbach
Mar 1, 1997·Microbiology·Susan F Koval, M E Bayer
Feb 24, 2001·Environmental Microbiology·H Reichenbach
May 29, 2002·Microbial Ecology·K.K. Rashidan, D.F. Bird
Sep 27, 2002·Chembiochem : a European Journal of Chemical Biology·Helge Björn BodeAxel Zeeck
Jun 28, 2003·FEMS Microbiology Reviews·Dietrich H Nies
Dec 23, 2003·Environmental Microbiology·Yair Shemesh, Edouard Jurkevitch
Jul 21, 2004·Nature Reviews. Microbiology·R Elizabeth Sockett, Carey Lambert
May 17, 2005·Colloids and Surfaces. B, Biointerfaces·Megan E NúñezEileen M Spain
Jun 9, 2005·Microbiology·Vinh D PhamMitchell Singer
Jul 8, 2005·Applied and Environmental Microbiology·Daniel E Kadouri, George A O'Toole
Aug 4, 2006·Journal of Bacteriology·James BerlemanJohn R Kirby
Oct 4, 2006·Proceedings of the National Academy of Sciences of the United States of America·B S GoldmanH B Kaplan
Nov 14, 2006·Applied and Environmental Microbiology·Daniel E KadouriGeorge A O'Toole
Apr 6, 2007·Microbial Ecology·Kristina L HilleslandGregory J Velicer
Apr 2, 2008·Applied and Environmental Microbiology·Daniel KrugRolf Müller
Oct 7, 2008·Proceedings of the National Academy of Sciences of the United States of America·Juana PérezJosé Muñoz-Dorado
Nov 28, 2008·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Helen W BoucherJohn Bartlett
Mar 3, 2009·Proceedings of the National Academy of Sciences of the United States of America·Ashvini ChauhanHenry N Williams
Mar 13, 2009·Journal of Dental Research·M Van EsscheW Teughels
Jun 13, 2009·FEMS Microbiology Reviews·James Berleman, John R Kirby
Jul 7, 2009·Annual Review of Microbiology·Renee Elizabeth Sockett
Jul 14, 2009·Genomics, Proteomics & Bioinformatics·Catharine SongMazen Saleh
Jan 12, 2010·PloS One·Carey LambertRenee Elizabeth Sockett
Mar 2, 2010·Nature Reviews. Microbiology·Heather K AllenJo Handelsman
Jun 4, 2010·Natural Product Reports·Kira J Weissman, Rolf Müller
Aug 31, 2010·Applied and Environmental Microbiology·Andrew D MorganGregory J Velicer
Sep 21, 2010·International Journal of Hygiene and Environmental Health·Natalia Y Markelova
Jan 11, 2011·Molecular Oral Microbiology·A Dashiff, Daniel E Kadouri
Jan 15, 2011·Clinical Microbiology Reviews·Lynn L Silver
Feb 18, 2011·The ISME Journal·Huan ChenHenry N Williams
Apr 9, 2011·Nature·Matthew A Cooper, David Shlaes
Jun 1, 2011·Chembiochem : a European Journal of Chemical Biology·Niña Socorro CortinaRolf Müller
Jun 28, 2011·Applied and Environmental Microbiology·Robert J AtterburyRenee Elizabeth Sockett
Jul 19, 2011·Journal of Bacteriology·Yao XiaoDaniel Wall
Sep 2, 2011·Nature·Vanessa M D'CostaGerard D Wright
Nov 4, 2011·Nature Reviews. Microbiology·Karen BushHelen I Zgurskaya
Mar 1, 2012·BMB Reports·Mohammed DwidarRobert J Mitchell
Mar 9, 2013·Microbiology and Molecular Biology Reviews : MMBR·Gang LiuHuarong Tan
May 1, 2013·Nature Reviews. Drug Discovery·Kim Lewis
Jul 16, 2013·Environmental Microbiology·Jonathan P RemisManfred Auer
Oct 4, 2013·The ISME Journal·Zohar PasternakEdouard Jurkevitch
Dec 24, 2013·Ecology·John N GriffinBradley J Cardinale
Feb 19, 2014·Archives of Microbiology·Charushila KumbharMilind Watve
Mar 7, 2014·Current Opinion in Biotechnology·Julia JohnkeAntonis Chatzinotas
Apr 23, 2014·FEMS Microbiology Ecology·Prem P KandelEdouard Jurkevitch
May 9, 2014·Future Microbiology·Robert M Q Shanks, Daniel E Kadouri
Jun 24, 2014·Annals of the New York Academy of Sciences·Heather K AllenThomas A Casey
Jul 9, 2014·Applied and Environmental Microbiology·Susanne MüllerJohn R Kirby
Sep 7, 2014·Applied and Environmental Microbiology·William H DePasMatthew R Chapman
Sep 25, 2014·Frontiers in Microbiology·James E BerlemanManfred Auer
Oct 19, 2014·Applied and Environmental Microbiology·Susanne MüllerJohn R Kirby
Dec 2, 2014·Nature Reviews. Microbiology·Jessica M A BlairLaura J V Piddock
Feb 18, 2015·Nature Chemical Biology·Chad W Johnston, Nathan A Magarvey
Mar 21, 2015·Proceedings of the National Academy of Sciences of the United States of America·Thomas P Van BoeckelRamanan Laxminarayan
Mar 31, 2015·Nature Reviews. Microbiology·Thomas U BerendonkJosé L Martínez
May 8, 2015·Nucleic Acids Research·Tilmann WeberMarnix H Medema
May 23, 2015·Natural Product Reports·Matthew F Traxler, Roberto Kolter
May 29, 2015·Nature·Sara Reardon
Jun 2, 2015·Frontiers in Microbiology·Sergio AntorazHéctor Rodríguez
Aug 10, 2015·Journal of Molecular Biology·Pengbo CaoDaniel Wall
Nov 1, 2015·Microbiology·Ryan Keane, James Berleman
Dec 15, 2015·Environmental Microbiology·Juana PérezJosé Muñoz-Dorado
Mar 2, 2016·Environmental Microbiology Reports·Ryan M ChanyiJoanna S Brooke
Apr 2, 2016·ACS Chemical Biology·Brandon L Findlay
Jun 9, 2016·Trends in Pharmacological Sciences·Mark G Moloney
Jun 16, 2016·Frontiers in Microbiology·José Muñoz-DoradoJuana Pérez
Jun 25, 2016·Beilstein Journal of Organic Chemistry·Juliane KorpMarkus Nett
Aug 17, 2016·Scientific Reports·Eric G RomanowskiRobert M Q Shanks
Sep 1, 2016·PloS One·Shilpi GuptaDaniel E Kadouri
Feb 13, 2015·ACS Infectious Diseases·Gerard D Wright
Sep 16, 2016·Scientific Reports·Ajay K MonnappaRobert J Mitchell
Nov 12, 2016·MBio·Kenneth ShatzkesDaniel E Kadouri
Nov 28, 2016·Current Biology : CB·Alexandra R WillisRenee Elizabeth Sockett
Dec 2, 2016·Natural Product Reports·J HerrmannRolf Müller
Dec 30, 2016·Environmental Microbiology Reports·Jess Tyson, R Elizabeth Sockett
Mar 7, 2017·Scientific Reports·Kenneth ShatzkesDaniel E Kadouri
Mar 10, 2017·Biotechnology Letters·C KealeyC B Brady
May 10, 2017·Future Microbiology·Kenneth ShatzkesDaniel E Kadouri
May 14, 2017·Scientific Reports·Kenneth ShatzkesNancy D Connell
May 16, 2017·Advanced Drug Delivery Reviews·Yehou M D GnopoDavid Putnam
Dec 26, 2017·The Lancet Infectious Diseases·Evelina TacconelliWHO Pathogens Priority List Working Group
Oct 8, 2018·Journal of Controlled Release : Official Journal of the Controlled Release Society·Eilien SchulzGregor Fuhrmann
Jan 27, 2019·Antibiotics·Pavan K MantravadiAnutthaman Parthasarathy
Jan 27, 2019·Trends in Microbiology·Chandradhish GhoshJayanta Haldar
Mar 29, 2019·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·Rupert C Marshall, David E Whitworth
May 12, 2019·Scientific Reports·James S FindlayPetra C F Oyston
Jun 13, 2019·Microbial Ecology·Julia JohnkeHinrich Schulenburg
Aug 24, 2019·Nature Microbiology·Sara Hernando-AmadoJosé L Martínez
Sep 4, 2019·The Science of the Total Environment·Magdalena PazdaEwa Mulkiewicz
Nov 14, 2019·Proceedings of the National Academy of Sciences of the United States of America·Jyoti Madhusoodanan
Feb 5, 2020·Frontiers in Microbiology·Susanne Thiery, Christine Kaimer
Feb 9, 2020·International Journal of Molecular Sciences·Chih-Hung WangCheng-Yen Kao
Mar 3, 2020·Frontiers in Microbiology·Francisco Javier Contreras-MorenoAurelio Moraleda-Muñoz
Mar 3, 2020·Frontiers in Microbiology·Jade A EzzedineStéphan Jacquet
Mar 21, 2020·Cell·Kim Lewis
May 1, 2020·Frontiers in Microbiology·Eleni BratanisEwa Bukowska-Faniband
May 7, 2020·Molecular Omics·Allison S ZwaryczDavid E Whitworth

Related Concepts

Antibiotics
Drug Resistance
Medicine
Problem
Reptiles
Research
Source
Agent
Axenic Culture
Microbicides

Related Feeds

Antimicrobial Resistance

Antimicrobial resistance poses a significant threat to the continued successful use of antimicrobial agents for the treatment of bacterial infections.

Antimicrobial Resistance (ASM)

Antimicrobial resistance poses a significant threat to the continued successful use of antimicrobial agents for the treatment of bacterial infections.

Related Papers

Current Biology : CB
Gregory J Velicer, Helena Mendes-Soares
The Journal of Antimicrobial Chemotherapy
Neil WoodfordUK Antibacterial Antisense Study Group
The American Journal of the Medical Sciences
Ronald A GreenfieldMichael S Bronze
Antonie van Leeuwenhoek
Jos M RaaijmakersJorge T de Souza
© 2021 Meta ULC. All rights reserved