The anticoagulant effect of heparan sulfate and dermatan sulfate

Thrombophilia includes conditions with increased tendency for excessive blood clotting. Blood clotting occurs when the body has insufficient amounts of specialized proteins that make blood clot and stop bleeding. Here is the latest research on blood clotting disorders.

The anticoagulant effect of heparan sulfate and dermatan sulfate

Abstract

References

Heparin cofactor activity measured with an amidolytic method

Relation of chemical of heparin to its anticoagulant activity

Heparin coupled to albumin, dextran and ficoll: influence on blood coagulation and platelets, and in vivo duration

Distribution of sulphate and iduronic acid residues in heparin and heparan sulphate

Distribution and composition of acid mucopolysaccharides in normal and atherosclerotic human aortas

Inhibition of atherosclerosis in cholesterol-fed rabbits by a heparitin sulfate. Preliminary communication

Coupling of glycosaminoglycans to agarose beads (sepharose 4B)

Chromatography of acidic glycosaminoglycans on DEAE-cellulose

Sulfated mucopolysaccharide synthesis and secretion in endothelial cell cultures

Heparin as inhibitor of mammalian protein synthesis. II. Degree of sulfation; related sulfated mucopolysaccharides

Progressive inactivation of purified factor VII by heparin and antithrombin III

Anticoagulant action of heparin

Properties of fractionated chondroitin sulphate from ox nasal septa

Antithrombin 3, antifactor Xa and heparin

Inhibition of the thrombin-fibrinogen reaction by heparin and purified cofactor

The specific assay of Prower-Stuart factor and factor VII

Studies on corneal polysaccharides. I. Separation

Determination of 2-deoxy-2-sulfoaminohexose content of mucopolysaccharides

Citations

Interaction of thrombin with antithrombin, heparin cofactor II, and protein C inhibitor

Tissue lipoprotein lipase activity and its action in lipoprotein metabolism

An experimental study of vascular damage in estrogen-induced embolization

Natural proteinase inhibitors: blood coagulation inhibition and evolutionary relationships

A comparison of the activity of a heparan sulphate of defined molecular weight range (7500-15,000 Da) with heparin and dermatan sulphate

The accumulation of circulating histones on heparan sulphate in the capillary glycocalyx of the lungs

Investigating serpin-enzyme complex formation and stability via single and multiple residue reactive centre loop substitutions in heparin cofactor II

Localization of heparin cofactor II in injured human skin: a potential role in wound healing

Inhibition of a thrombin anion-binding exosite-2 mutant by the glycosaminoglycan-dependent serpins protein C inhibitor and heparin cofactor II

Amino acid residues of heparin cofactor II required for stimulation of thrombin inhibition by sulphated polyanions

Epidemiology and pathogenesis of venous thrombosis

Reactivation of unstable angina after the discontinuation of heparin

Rat hepatocytes in serum-free primary culture elaborate an extensive extracellular matrix containing fibrin and fibronectin

Studies of natural anticoagulant proteins and anticardiolipin antibodies in patients with the lupus anticoagulant

Involvement of heparin cofactor II in chymotrypsin neutralization and in the pancreatic proteinase-antiproteinase interaction during acute pancreatitis in man

The heparin and pentosan polysulfate binding sites of human antithrombin overlap but are not identical.

Modulation of heparin cofactor II activity by histidine-rich glycoprotein and platelet factor 4

Placental dermatan sulfate: isolation, anticoagulant activity, and association with heparin cofactor II

Accelerated atherogenesis and neointima formation in heparin cofactor II deficient mice

Vascular dermatan sulfate regulates the antithrombotic activity of heparin cofactor II

Heparin modulation of human plasma kallikrein on different substrates and inhibitors

Factors associated with bleeding in elderly hospitalized patients treated with enoxaparin sodium : a prospective, open-label, observational study.

Mesoglycan: clinical evidences for use in vascular diseases

Marine Origin Polysaccharides in Drug Delivery Systems

Dermatan sulfate and bone marrow mononuclear cells used as a new therapeutic strategy after arterial injury in mice

Characterization of a novel dermatan sulfate with high antithrombin activity from ray skin (Raja radula)

Circulating heparin-like anticoagulants: report of five consecutive cases and a review

Uptake and inactivation of thrombin by the fresh, glutardialdehyde or heparin treated human umbilical cord vein endothelium

Heparin with low affinity to antithrombin III inhibits the activation of prothrombin in normal plasma

Assay of dermatan sulfate cofactor (heparin cofactor II) activity in human plasma

Heparan structure and the modulation of angiogenesis

Effect of glycosaminoglycans on thrombin-induced clotting of normal and antithrombin III-deficient plasmas

Glycosaminoglycans and the control of cell surface proteinase activity

Anticoagulant activity of heparin: assay of bovine, human and porcine preparations by amidolytic and clotting methods

Neutralization of dermatan sulfate in vitro and in vivo by protamine sulfate and polybrene

Consumption of heparin cofactor II (dermatan sulfate cofactor) and antithrombin during coagulation

The anticoagulant activity of dermatan sulphates

Enhancement of antithrombin III activity by carrageenans

Anti-factor Xa activity of heparan sulphate.

Fractionation of heparin by chromatography on immobilized thrombin. Correlation between the anticoagulant activity of the fractions and their content of heparin with high affinity for antithrombin

Binding of platelet factor 4 to cultured human umbilical vein endothelial cells

The inhibition of thrombin and chymotrypsin by heparin-cofactor II.

Studies on the binding of heparin to prothrombin and thrombin and the effect of heparin-binding on thrombin activity

Effects of subcutaneously administered dermatan sulfate (MF 701) on the coagulation and fibrinolytic parameters of healthy volunteers

The anticoagulant effect of chondroitin-4-sulfate

Elevated levels of thrombin-heparin cofactor II complex in plasma from patients with disseminated intravascular coagulation

Anticoagulant properties of semisynthetic polysaccharide sulfates

Inhibition of thrombin by antithrombin III in the presence of certain glycosaminoglycans found in the mammalian aorta

Effect of sulphated polysaccharides on the alpha 1-antitrypsin inhibition of amidolysis catalysed by coagulation cascade proteinases

The anticoagulant activity of dermatan sulphates: evidence against the involvement of antithrombin III

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