The antifungal activity of Artemisia sieberi essential oil from different localities of Iran against dermatophyte fungi

Journal de mycologie médicale
M Mahboubi, N Kazempour

Abstract

Dermatophyte fungi are the most common cause of dermatophytosis in humans and animals. Artemisia sieberi is traditionally used for treatment of fungi related skin infections. In this investigation, we analyzed five samples of A. sieberi oils (different harvesting times and distinctive collecting locations) by GC-FID and GC-MS. The antifungal activities of A. sieberi oils were evaluated against different dermatophytes. The anti-elastase activities of essential oils were also evaluated. The results of analysis showed that the harvesting time and collecting location can affect the chemical compositions and oil yields. The best time for collecting the A. sieberi with high yield was spring season (January-February). There was no significant difference between the desirable anti-dermatophyte activities of A. sieberi oils with different chemical compositions. M. gypseum, T. rubrum and M. canis had more sensitivity than others to A. sieberi oils. The oils with higher amounts of α-thujone, β-thujone showed the higher anti-elastase activity. Therefore, A. sieberi can be used as topical antifungal agent for treatment of skin dermatophyte infections.

References

Nov 1, 2002·Journal of Clinical Microbiology·Belkys Fernández-TorresJosep Guarro
Dec 7, 2006·Journal of Cosmetic Dermatology·Masahiro MoriKazuhito Watabe
May 29, 2008·International Journal of Cosmetic Science·A BenaigesE Gironés
Dec 1, 1995·International Journal of Cosmetic Science·V Bizot-FoulonW Hornebeck

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Citations

Jul 23, 2016·BioMed Research International·Han Chien LinShao-Hung Wang
Mar 14, 2019·Mini Reviews in Medicinal Chemistry·Zahra Tayarani-NajaranSeyed Ahmad Emami
Nov 8, 2017·Letters in Applied Microbiology·A M FuentefriaS F de Andrade
Mar 7, 2021·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Aswir Abd RashedAhmad Zuhairi Abd Rahman

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