Abstract
Annona emarginata (Schltdl.) H. Rainer, commonly known as "arachichú", "araticú", "aratigú", and "yerba mora", is a plant that grows in Argentina. Infusions and decoctions are used in folk medicine as a gargle against throat pain and for calming toothache; another way to use the plant for these purposes is chewing its leaves. Extracts from bark, flowers, leaves, and fruits from A. emarginata were subjected to antibacterial assays against a panel of Gram (+) and Gram (-) pathogenic bacteria according to Clinical and Laboratory Standards Institute protocols. Extracts from the stem bark and leaves showed moderate activity against the bacteria tested with values between 250⁻1000 µg/mL. Regarding flower extracts, less polar extracts (hexane, dichloromethane) showed very strong antibacterial activity against methicillin-sensitive Staphylococcus aureus ATCC 25923 and methicillin-resistant S. aureus ATCC 43300 with values between 16⁻125 µg/mL. Additionally, hexane extract showed activity against Klebsiella pneumoniae (MIC = 250 µg/mL). The global methanolic extract of the fruits (MeOHGEF) was also active against the three strains mentioned above, with MICs values 250⁻500 µg/mL. Bioassay-guided fractionation of MeOHGEF led to the isolat...Continue Reading
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Citations
Aug 9, 2018·International Journal of Molecular Sciences·Sarka PospisilovaJosef Jampilek
Jun 5, 2019·Medicinal Chemistry·Robert Musiol
Sep 13, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Jiri KosJosef Jampilek
Jan 19, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Wioleta CieslikRobert Musiol
Jul 18, 2018·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Annabelle St-PierreIsabel Desgagné-Penix
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