The Antioxidant and Antihyperglycemic Activities of Bottlebrush Plant (Callistemon lanceolatus ) Stem Extracts

Medicines
Ramesh KumarAbhay K Pandey

Abstract

Background: Diabetes mellitus, a metabolic disease, is a major health concern today throughout the world. Callistemon lanceolatus (Myrtaceae), commonly known as bottlebrush, has been used by Indian tribal communities for the treatment of many diseases. The purpose of this study was to explore antioxidant and antihyperglycemic potential of methanolic and aqueous extracts of the stem of C. lanceolatus in vitro and in vivo. Methods: Phytoconstituents of C. lanceolatus stem were extracted in methanol and water sequentially followed by phytochemical analysis. The in vitro antioxidant potential of aqueous and methanolic extracts was assessed by metal ion chelating, free radical scavenging, and reducing power assays. The in vivo antihyperglycemic activity of the oral methanolic extract was studied in alloxan-induced diabetic rats. Bodyweight and blood glucose were monitored regularly. After the treatment period, serum was examined for total cholesterol, triglycerides, high-density lipoprotein (HDL), bilirubin, creatinine, urea, glutamate pyruvate transaminase (SGPT), glutamate oxaloacetate transaminase (SGOT), and alkaline phosphatase (ALP). Results: Methanolic extract exhibited superior antioxidant activity to aqueous extract. A mark...Continue Reading

References

Jan 5, 2002·Journal of Agricultural and Food Chemistry·R P SinghG K Jayaprakasha
Jun 18, 2002·Journal of Ethnopharmacology·Natalya ChistokhodovaD Howard Miles
Jun 27, 2009·Archives of Pharmacal Research·Wonsik JeongDongho Lee
May 24, 2011·Ophthalmology·Miho YasudaTatsuro Ishibashi
Oct 19, 2011·Experimental and Toxicologic Pathology : Official Journal of the Gesellschaft Für Toxikologische Pathologie·Adedayo O Ademiluyi, Ganiyu Oboh
Sep 25, 2012·Fitoterapia·Syed NazreenMohammad Sarwar Alam
Jun 1, 2013·BMC Complementary and Alternative Medicine·Shashank KumarAbhay K Pandey
Jan 29, 2014·TheScientificWorldJournal·Shashank Kumar, Abhay K Pandey
May 18, 2016·Applied Biochemistry and Biotechnology·Daljit Singh AroraHarpreet Kaur
Jun 2, 2016·BMC Complementary and Alternative Medicine·Uma Kant SharmaAbhay K Pandey
Aug 31, 2017·African Journal of Traditional, Complementary, and Alternative Medicines : AJTCAM·Chidinma A OkoloAugustine N Okorie
Oct 17, 2017·Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie·Jin-Jun WangXiao-Jie Ni
Feb 1, 2018·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Abu Sadat Md SayemChowdhury Faiz Hossain
Apr 14, 2018·3 Biotech·Uma Kant SharmaAbhay K Pandey
Jun 6, 2018·PloS One·Janielle da Silva Melo da CunhaKely de Picoli Souza
Aug 19, 2018·Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie·Kamal AhmadFareeda Athar
Feb 11, 2019·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Uma Kant SharmaAbhay Kumar Pandey
Mar 28, 2019·Journal of Cellular Physiology·Tanuj JoshiMohammad H Farzaei
Jun 14, 2019·Journal of Diabetes Research·Julia M Dos SantosRoberta H Mendes

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BETA
glycosylation

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GraphPad
Graphpad Prism

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