PMID: 15376391Sep 21, 2004Paper

The antitumor activities of the extracts from Stellera chamaejasmel L. in vitro by means of systematic solvent extraction

Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials
Bin WangRuxue Zhang

Abstract

To screen the antitumor extract from Stellera chamaejasmel L.. The means of systematic solvent extraction was used to separate the 95% ethanol extract. The antitumor activities of the different extracts in vitro were analyzed with MTT assay. The petroleum ether extract and the chloroform extract strongly inhibited cell proliferation of human cancer cell lines such as leukemia HL-60, stomach cancer SGC-7901 and hepatocarcinoma BEL-7402, and showed significant dose-dependent response while the n-butanol extract and the methanol extract exhibited low antitumor activities in vitro. The petroleum ether extract was most active. The petroleum ether extract is the principal antitumor extract from Stellera chamaejasmel L..

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