The Application of Deep Learning in Cancer Prognosis Prediction

Cancers
Wan ZhuXiangqian Guo

Abstract

Deep learning has been applied to many areas in health care, including imaging diagnosis, digital pathology, prediction of hospital admission, drug design, classification of cancer and stromal cells, doctor assistance, etc. Cancer prognosis is to estimate the fate of cancer, probabilities of cancer recurrence and progression, and to provide survival estimation to the patients. The accuracy of cancer prognosis prediction will greatly benefit clinical management of cancer patients. The improvement of biomedical translational research and the application of advanced statistical analysis and machine learning methods are the driving forces to improve cancer prognosis prediction. Recent years, there is a significant increase of computational power and rapid advancement in the technology of artificial intelligence, particularly in deep learning. In addition, the cost reduction in large scale next-generation sequencing, and the availability of such data through open source databases (e.g., TCGA and GEO databases) offer us opportunities to possibly build more powerful and accurate models to predict cancer prognosis more accurately. In this review, we reviewed the most recent published works that used deep learning to build models for ca...Continue Reading

References

Oct 23, 1997·Neural Computation·S Hochreiter, J Schmidhuber
Dec 26, 2001·Nucleic Acids Research·Ron EdgarAlex E Lash
Aug 27, 2005·IEEE Transactions on Pattern Analysis and Machine Intelligence·Hanchuan PengChris Ding
Sep 1, 2005·Lifetime Data Analysis·Michael P Jones, Bongin Yoo
Dec 31, 2005·Nucleic Acids Research·Adil ElfilaliEmmanuel Barillot
Feb 14, 2007·Molecular Cancer·Farid E AhmedDon Holbert
Apr 4, 2013·Science Signaling·Jianjiong GaoNikolaus Schultz
May 30, 2013·Nature Genetics·UNKNOWN GTEx Consortium
Sep 28, 2013·Nature Genetics·UNKNOWN Cancer Genome Atlas Research NetworkJoshua M Stuart
Oct 30, 2013·Journal of Clinical Bioinformatics·Chirayu Pankaj Goswami, Harikrishna Nakshatri
Jan 8, 2014·Journal of Diabetes and Metabolic Disorders·Payam Farahbakhsh-FarsiAbolghassem Djazayery
Feb 11, 2014·Computers in Biology and Medicine·Yi-Zeng HsiehPa-Chun Wang
Feb 19, 2015·Contemporary Oncology Współczesna Onkologia·Katarzyna TomczakMaciej Wiznerowicz
Mar 10, 2015·Computational and Structural Biotechnology Journal·Konstantina KourouDimitrios I Fotiadis
May 15, 2015·Pain·Choong-Wan Woo, Tor D Wager
Aug 8, 2015·Science Translational Medicine·Katharine E HenrySuchi Saria
Mar 13, 2016·Briefings in Bioinformatics·Chen MengAedín C Culhane
Mar 24, 2016·Methods in Molecular Biology·Emily Clough, Tanya Barrett
Oct 28, 2016·PloS One·Uma R ChandranRebecca S Jacobson
Jan 8, 2017·Database : the Journal of Biological Databases and Curation·Mario DengSven Perner
Feb 6, 2017·Journal of Experimental Botany·Piers A Hemsley
Aug 2, 2017·Neurobiology of Aging·Sulantha MathotaarachchiUNKNOWN Alzheimer's Disease Neuroimaging Initiative
Aug 9, 2017·Journal of Digital Imaging·Panagiotis KorfiatisBradley J Erickson
Oct 7, 2017·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Kumardeep ChaudharyLana X Garmire
Dec 22, 2017·Scientific Reports·Adityanarayanan RadhakrishnanG V Shivashankar
Feb 23, 2018·Scientific Reports·Dmitrii BychkovJohan Lundin
Feb 28, 2018·BMC Medical Research Methodology·Jared L KatzmanYuval Kluger
Mar 14, 2018·Proceedings of the National Academy of Sciences of the United States of America·Pooya MobadersanyLee A D Cooper
Mar 27, 2018·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Jeeheh OhJenna Wiens
Apr 11, 2018·PLoS Computational Biology·Travers ChingLana X Garmire
Jun 16, 2018·Cell·Michael K YuTrey Ideker
Jul 11, 2018·Journal of Medical Internet Research·Laurent Cleret de LangavantKristine Yaffe
Jul 12, 2018·IEEE/ACM Transactions on Computational Biology and Bioinformatics·Dongdong SunAo Li
Nov 6, 2018·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Shuo WangJie Tian
Nov 9, 2018·Nucleic Acids Research·Maximilian HaeusslerW James Kent

❮ Previous
Next ❯

Citations

Jun 20, 2020·Clinical Pharmacology and Therapeutics·Sebastien Benzekry
Oct 1, 2020·Computational and Structural Biotechnology Journal·Erik Meijering
Nov 18, 2020·Journal of Personalized Medicine·Amin Zadeh ShiraziGuillermo A Gomez
Dec 31, 2020·International Journal of Molecular Sciences·Ivana FridrichovaKarol Kajo
Aug 1, 2020·Canadian Association of Radiologists Journal = Journal L'Association Canadienne Des Radiologistes·Jaryd R ChristieSarah A Mattonen
Apr 2, 2021·Biotechnology Advances·Parminder S ReelEmily Jefferson
Apr 7, 2021·Molecular Biology Reports·Alieh FarshbafNooshin Mohtasham
Apr 16, 2021·The Journal of Clinical Investigation·Toby C Cornish
Apr 15, 2021·International Journal of Cancer. Journal International Du Cancer·Sung Hak LeeHyun-Jong Jang
May 1, 2021·International Journal of Molecular Sciences·Antonio Jesús Banegas-LunaHoracio Pérez-Sánchez
May 1, 2021·Diagnostics·Rima HajjoAlexander Tropsha
Jul 1, 2021·Scientific Reports·Luís A Vale-Silva, Karl Rohr
Jul 20, 2021·Frontiers in Immunology·Charlotte DomblidesMarie-Caroline Dieu-Nosjean
Jul 22, 2021·Computational and Structural Biotechnology Journal·Milan PicardArnaud Droit
Aug 12, 2021·Computational and Structural Biotechnology Journal·Raihan RafiqueJulhash U Kazi
Aug 30, 2021·International Journal of Medical Informatics·John AdeoyePeter Thomson

❮ Previous
Next ❯

Methods Mentioned

BETA
RNAseq
proteomic profiling
feature extraction
biopsy

Software Mentioned

nnet
Cox
DeepSurv
cBioPortal genome browser ( Xena )
TCGA
RankDeepSurvival
PASNet
FIREHOSE
lmQCM
MDNNMD

Related Concepts

Related Feeds

Cancer Sequencing

Several sequencing approaches are employed to understand and examine tumor development and progression. These include whole genome as well as RNA sequencing. Here is the latest research on cancer sequencing.