The application of human anterior lens capsule autotransplantation in phacotrabeculectomy: a prospective, comparative and randomized clinical study

Eye
D LuJ Ji

Abstract

To determine whether the autotransplantation of human anterior lens capsule (ALC) in the trabeculectomy site can aid filtration. We conducted a prospective, randomized, and masked clinical trial to evaluate the outcome of human ALC autotransplantation in phacotrabeculectomy. Fifty patients with coexisting cataract and uncontrolled glaucoma despite maximum medical therapy were enrolled in this study. In the ALC group, combined phacoemulsification, posterior chamber intraocular lens implantation, and trabeculectomy were performed in 29 eyes, the anterior lens capsule was then put under the scleral tunnel. In the mitomycin-C (MMC) group, phacoemulsification, posterior chamber intraocular lens implantation, and trabeculectomy were performed in 21 eyes, MMC was used intraoperatively. Follow-up period was 12 months. The appearance of filtering bleb, intraocular pressure, and best corrected visual acuity were evaluated. (1) There was no statistical difference between the ALC group and the MMC group in the formation of functional filtering blebs (chi(2)=0.132, P>0.05), intraocular pressure (t=0.007, P>0.05), the number of antiglaucoma medications (Z=-0.800, P>0.05), and best corrected visual acuity (chi(2)=0.055, P>0.05). (2) The anter...Continue Reading

References

Jan 1, 1992·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·B C Chauhan, S M Drance
Oct 1, 1968·American Journal of Ophthalmology·J E Cairns
Sep 15, 1993·American Journal of Ophthalmology·P T ZachariaJ S Schuman
Apr 1, 1996·Ophthalmology·E J HigginbothamG L Skuta
Aug 1, 1996·Archives of Ophthalmology·D S GreenfieldH W Flynn
Nov 14, 1997·Journal of Cataract and Refractive Surgery·M AnwarA el-Maghraby
Dec 14, 1999·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·U HartmannU H Steinhorst
Oct 12, 2000·Eye·M F CordeiroP T Khaw
Feb 27, 2001·Current Opinion in Ophthalmology·P T KhawM F Cordeiro
Mar 30, 2001·The Journal of Biological Chemistry·Y MaeshimaR Kalluri
Jun 16, 2001·The Journal of Biological Chemistry·Y MaeshimaR Kalluri
Mar 22, 2002·Acta Ophthalmologica Scandinavica·Jens Folke KiilgaardMorten la Cour
Jul 3, 2002·Ophthalmology·Rajiv BindlishRichard Lehrer
Sep 25, 2002·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·G KrommesF Grehn
Jun 5, 2003·Acta Ophthalmologica Scandinavica·Carlo CaginiRaffaella Gallai
Apr 27, 2005·Investigative Ophthalmology & Visual Science·Noël M ZiebarthJean-Marie Parel

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Citations

May 3, 2011·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Charles N Serhan
Apr 27, 2012·Medical Science Monitor : International Medical Journal of Experimental and Clinical Research·Małgorzata NitaUrszula Mazurek
Aug 19, 2010·Journal of Glaucoma·Ahmed M Emarah, Mostafa Aly El-Helw
Dec 10, 2009·Current Opinion in Ophthalmology

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