The application of nonlinear metrics to assess organization differences in short recordings of paroxysmal and persistent atrial fibrillation

Physiological Measurement
Raúl Alcaraz, José Joaquín Rieta

Abstract

Atrial fibrillation (AF) is the most common arrhythmia in clinical practice. In the first stages of the disease, AF may terminate spontaneously and it is referred to as paroxysmal AF. The arrhythmia is called persistent AF when external intervention is required to its termination. In the present work, a method to non-invasively assess AF organization has been applied to discern between paroxysmal and persistent AF episodes at any time. Previous works have suggested that the probability of AF termination is inversely related to the number of reentries wandering throughout the atrial tissue. Given that it has also been hypothesized that the number of reentries is directly correlated with AF organization, a fast and robust method able to assess organization differences in AF could be of great interest. In fact, the distinction between paroxysmal and persistent episodes in patients without previously known AF history, making use of short ECG recordings, could contribute to taking earlier decisions on AF management in daily clinical practice, without the need to require 24 h or 48 h Holter recordings. The method was based on a nonlinear regularity index, such as sample entropy (SampEn), and evidenced to be a significant discriminato...Continue Reading

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Citations

Mar 10, 2012·Medical & Biological Engineering & Computing·Luigi Y Di MarcoPhilip Langley
Feb 7, 2012·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Laurent UldryJean-Marc Vesin
Mar 17, 2012·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Ulrich SchottenStef Zeemering
Jan 14, 2011·Medical Engineering & Physics·Raúl AlcarazJosé Joaquín Rieta
Feb 15, 2011·IEEE Transactions on Bio-medical Engineering·Raúl AlcarazJosé Joaquín Rieta

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