Abstract
Large-artery atherosclerotic stroke (LAAs) is related to carotid plaque, but the mechanical mechanism is unclear. We aimed to use ultrasonic velocity vector imaging (VVI) technique to study the mechanical difference of carotid plaque in patients with LAAs and controls. We enrolled 43 LAAs patients and 38 controls but all showing plaque on carotid ultrasonography. Ultrasonic VVI technique was used to analyze radial systolic and diastolic peak velocity (R-vs, R-vd), radial and circumferential peak strain (R-s, C-s) and radial displacement (R-dis) of carotid plaque. Compared with controls, LAAs patients showed higher pulse pressure (P = .001), pulse pressure index (PPI, P = .006), and greater stress at carotid plaque as manifested by higher absolute value of radial diastolic peak velocity (R-vd, P = .021), radial systolic peak velocity (R-vs, P = .007), radial peak strain (R-s, P = .015), and radial displacement (R-dis, P = .022). PPI was significantly correlated with R-vs (r = -.274, P = .013), R-vd (r = .304, P = .006), and R-dis (r = -.28, P = .011). But there was no correlation between R-s and blood pressure. R-s was screened to be the most predictable parameters for LAAs (odds ratio, 1.118; 95% confidence interval, 1.012∼1.23...Continue Reading
References
Jun 1, 1982·The British Journal of Surgery·R J LusbyR N Baird
Jan 1, 1993·Stroke; a Journal of Cerebral Circulation·H P AdamsE E Marsh
Apr 1, 1993·Circulation·G C ChengR T Lee
Jun 19, 2002·Circulation·M HollanderM M B Breteler
Dec 22, 2004·Hypertension·Thomas G PickeringUNKNOWN Subcommittee of Professional and Public Education of the American Heart Association Council on High Blood Pressure Research
Aug 10, 2005·Neurology·J F FairheadP M Rothwell
Mar 14, 2007·Journal of Vascular Surgery·Zhi-Yong LiJonathan H Gillard
Feb 24, 2009·Medical Hypotheses·Yang Peng-Lin, Li Yue-Chun
May 26, 2009·Journal of Biomechanics·Hao GaoZhi-Yong Li
Feb 13, 2010·Atherosclerosis·Lei ZhangYun Zhang
Mar 13, 2010·Stroke; a Journal of Cerebral Circulation·Samuel A ThrysøeJens Vinge Nygaard
Jul 24, 2010·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Johan PetriniMaria J Eriksson
Aug 21, 2010·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·U SadatJ H Gillard
Oct 19, 2010·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·U SadatJ H Gillard
Nov 3, 2010·Circulation·Jaywant P ParmarChristopher M Kramer
Mar 29, 2011·Atherosclerosis·Sara Svedlund, Li-ming Gan
Aug 10, 2011·Journal of Biomechanics·Hao GaoZhi-Yong Li
Dec 22, 2011·Journal of Atherosclerosis and Thrombosis·Hyo Eun ParkDae-Won Sohn