The appropriate treatment of chronic pain

Clinical Drug Investigation
Piercarlo Sarzi-PuttiniDiego Fornasari

Abstract

Chronic pain is a common healthcare problem worldwide that ranks as a predominant reason for consulting a physician, yet effective management of chronic pain remains suboptimal, often resulting in unnecessary suffering and decreased quality of life, lost productivity and excessive healthcare costs. To overcome the challenges associated with the management of chronic pain, increased awareness and both patient and physician education are required. Improving physician knowledge of pain assessment and management guided by recommendations for a comprehensive, multifactorial, personalised treatment approach involving pharmacological and non-pharmacological approaches is key to achieving effective pain relief. Guidelines for the management of non-cancer and cancer pain recommend thorough patient assessment before individualized therapy based on the type and intensity of pain. The availability of mechanism-specific analgesics has facilitated improvements in the treatment of chronic non-cancer pain, which may be of neuropathic, muscle, inflammatory, mechanical/compressive or mixed origin. Stepwise escalation of analgesic therapy (paracetamol, non-steroidal anti-inflammatory drugs, mild to strong opioids) according to the World Health Or...Continue Reading

References

Dec 4, 2001·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·C MiaskowskiK Schumacher
Dec 23, 2003·Current Medical Research and Opinion·Cathy Stannard, Martin Johnson
Feb 21, 2004·Journal of the American College of Cardiology·Patricia A Howard, Patrice Delafontaine
Aug 13, 2005·European Journal of Pain : EJP·Harald BreivikDerek Gallacher
Jun 21, 2007·Anesthesia and Analgesia·Frank BrennanMichael Cousins
Aug 1, 2007·Journal of Pain and Symptom Management·Roelien H EntingPeter A E Sillevis Smitt
Feb 28, 2008·Drug Development and Industrial Pharmacy·Dave A MillerRobert O Williams
Jul 18, 2008·Annals of Oncology : Official Journal of the European Society for Medical Oncology·S DeandreaG Apolone
Feb 4, 2009·The Journal of Pain : Official Journal of the American Pain Society·Roger ChouUNKNOWN American Pain Society-American Academy of Pain Medicine Opioids Guidelines Panel
Oct 13, 2009·Pain Medicine : the Official Journal of the American Academy of Pain Medicine·Megan Crowley-MatokaDiana J Burgess
Aug 14, 2010·Pain·Nanna Brix FinnerupTroels Staehelin Jensen
Sep 30, 2010·Journal of the National Comprehensive Cancer Network : JNCCN·Robert SwarmUNKNOWN NCCN Adult Cancer Pain
Oct 30, 2010·Pain Medicine : the Official Journal of the American Academy of Pain Medicine·Carole C UpshurRoger Luckmann
Feb 22, 2011·Pain Medicine : the Official Journal of the American Academy of Pain Medicine·Michael E Schatman
Mar 18, 2011·Pain Practice : the Official Journal of World Institute of Pain·Alessandra GraziottinMichael N Berliner
Jun 8, 2011·Journal of Clinical Psychology·Mark A LumleyFrancis J Keefe
Oct 20, 2011·Annals of Oncology : Official Journal of the European Society for Medical Oncology·C I RipamontiUNKNOWN ESMO Guidelines Working Group
Mar 6, 2012·Clinical Drug Investigation·Renato Vellucci
Mar 6, 2012·Clinical Drug Investigation·Diego Fornasari

❮ Previous
Next ❯

Citations

Sep 27, 2013·Expert Opinion on Pharmacotherapy·Paul Farquhar-Smith, Anthony Gubbay
Aug 29, 2014·Current Medical Research and Opinion·Carmelo Scarpignato, Luigi Gatta
Aug 1, 2015·Journal of Neurosurgery·Erich Talamoni FonoffManoel Jacobsen Teixeira
Mar 13, 2014·Pain Medicine : the Official Journal of the American Academy of Pain Medicine·Dennis C TurkMyoung Kim
Jun 12, 2013·Journal of the American Medical Directors Association·Albert LukasMichael D Denkinger
Aug 13, 2015·Best Practice & Research. Clinical Rheumatology·Piercarlo Sarzi-PuttiniSerge Perrot
Mar 14, 2013·Nursing & Health Sciences·Nimet OvayoluAlper Sevinç
Jun 12, 2013·Pain Practice : the Official Journal of World Institute of Pain·Joost L M JongenCraig T Hartrick
Aug 13, 2015·Best Practice & Research. Clinical Rheumatology·Jacob N Ablin, Dan Buskila
May 10, 2015·Neuroscience and Biobehavioral Reviews·Lincoln M TracyMelita J Giummarra
Jun 18, 2014·Progress in Orthodontics·Iacopo CioffiAmbrosina Michelotti
Oct 18, 2016·Pain Research & Management : the Journal of the Canadian Pain Society = Journal De La Société Canadienne Pour Le Traitement De La Douleur·Anaïs LacasseManon Choinière
Dec 19, 2015·International Journal of Psychiatry in Medicine·David R SpiegelOlivia Raulli
Dec 7, 2017·Frontiers in Pharmacology·Marcos F DosSantosAlexandre F DaSilva
Feb 28, 2018·Trials·Carlos Suso-RiberaAzucena García-Palacios
Jul 25, 2019·Health and Quality of Life Outcomes·C Suso-RiberaA García-Palacios
Dec 5, 2014·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·Hance ClarkeZe'ev Seltzer
Feb 29, 2020·Journal of Pain Research·Juan YangLizu Xiao
Mar 20, 2013·Advances in Skin & Wound Care·Elena PopeR Gary Sibbald
Aug 15, 2020·Indian Journal of Anaesthesia·Babita GhaiSukhminder Jit Singh Bajwa
Apr 22, 2015·Cellular and Molecular Life Sciences : CMLS·Jialie LuoHongzhen Hu
Jul 6, 2018·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Dayna L AverittAnne Z Murphy
Aug 27, 2019·SAGE Open Nursing·Geraldine MartorellaLaurie Abbott

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Clinical Drug Investigation
Piercarlo Sarzi-PuttiniDiego Fornasari
Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego
Renata CwiekBarbara Lisowska
Critical Reviews in Oncology/hematology
Carla Ripamonti, Elena Bandieri
European Journal of Pain : EJP
J J Collins
© 2022 Meta ULC. All rights reserved