The arthropathy of fibroblastic rheumatism

Arthritis and Rheumatism
E RomasT Woodruff

Abstract

Fibroblastic rheumatism (FR) is a relatively rare syndrome characterized by the association of multiple cutaneous nodules with polyarthritis. The unique histologic finding in the skin and synovium of patients with FR is a proliferation of myofibroblast-like cells within a background matrix of collagen. The occurrence of erosive arthritis has not been emphasized in previous descriptions of FR. We describe a patient with FR who presented with symmetric polyarthritis, skin thickening, and dermal nodules. Despite treatment with prednisone and D-penicillamine, he developed a progressive, destructive polyarthropathy that mimicked multicentric reticulohistiocytosis.

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Citations

Mar 4, 1998·Arthritis and Rheumatism·T N Helm, K F Helm
Apr 29, 1998·Arthritis and Rheumatism·F SchiavonS Todesco
Nov 20, 2002·Pediatric Dermatology·Joyce M LeeMarilyn G Liang
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Oct 7, 2021·Rheumatology International·A PietaP V Voulgari

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