The assessment of multifocal ERG responses in school-age children with history of prematurity

Documenta Ophthalmologica. Advances in Ophthalmology
Marta MichalczukMałgorzata Krętowska

Abstract

The authors examined macular function in preterm-born children, using multifocal ERG (mfERG). Possible alterations in P1 amplitudes, P1 amplitudes density and P1 implicit time between school-age children with history of prematurity and their peers were researched. The correlations between parameters of mfERG responses and birth weight, gestational age, macular volume and central macular thickness were verified. A group of 18 preterm-born school-age children were analyzed (mean age 10.18 ± 1.21 years). The study group was compared to the group of 15 peers born appropriate for gestational age (mean age 10.8 ± 1.52 years). The mfERG was evaluated in all children. There were statistically significant differences for P1 amplitudes from ring 1 (p = 0.0001) and P1 amplitudes density from ring 1 (p = 0.0001). Calculating the correlation coefficients, we receive significant results for P1 amplitudes from ring 1 versus gestational age (r = 0.54; p = 0.026), birth weight (r = 0.54; p = 0.026) and central macular thickness (r = -0.62; p = 0.008), and for P1 amplitudes density from ring 1 versus central macular thickness (r = -0.51; p = 0.034). The study suggests that P1 amplitudes and P1 amplitudes density vary in preterm-born children in ...Continue Reading

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Citations

Sep 28, 2016·Progress in Retinal and Eye Research·Ronald M HansenAnne B Fulton
Jan 20, 2017·The British Journal of Ophthalmology·Lina H RaffaMarita Andersson Grönlund
Apr 18, 2019·Investigative Ophthalmology & Visual Science·Wadim BowlMonika Andrassi-Darida

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