PMID: 6672538Jan 1, 1983

The assessment of postmenopausal osteoporosis by total body neutron activation analysis

Metabolic Bone Disease & Related Research
R EastellP Tothill


Total body calcium (TBCa) was measured using a cyclotron for in vivo neutron activation analysis (IVNAA) in 20 healthy women, 15 women with vertebral compression fractures, and 8 women with wrist fractures. The precision of the technique, using phantoms, was 1.8% for a dose of 13 mSv. A formula for predicted TBCa (TBCap) was derived from the 20 normal women based on span and years postmenopause. The coefficient of variation of TBCa after normalization in the normal women was 6.6%. The mean TBCa values for the vertebral and wrist fracture groups were 69% and 84% of TBCap for women at the time of the menopause. The low TBCa in the wrist fracture group was attributable to post-menopausal bone loss. Of the low TBCa in the vertebral fracture group, about half the loss could be attributed to postmenopausal age and half to other factors.


Mar 1, 1979·The British Journal of Radiology·J R WilliamsC J Parnell
Apr 1, 1979·Annals of the Rheumatic Diseases·A C KennedyJ K Haywood
Mar 1, 1977·Metabolism: Clinical and Experimental·C H ChesnutJ D Denney
Jan 1, 1976·Metabolism: Clinical and Experimental·S H CohnK J Ellis
May 1, 1982·Physics in Medicine and Biology·N S KennedyP Tothill


Sep 1, 1993·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·A M SchottP J Meunier
Jan 1, 1986·Journal of the Royal Society of Medicine·D M Reid

Related Concepts

Neutron Activation Analysis
Post-Traumatic Osteoporosis
Spinal Injuries
Wrist Injuries

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