PMID: 8599039Dec 1, 1995Paper

The association between a cerebrovascular accident and peripheral arterial disease: a case-control study in Asturias, Spain

Revista clínica española
M Caicoya Gómez-MoránT Rodríguez Alvarez

Abstract

To evaluate peripheral arterial disease (PAD) and total stroke, cortical infarction, deep infarction and cerebral hemorrhage. The different manifestations of atherosclerotic disease, despite being considered a systemic disease, have different risk factors and complex associations between themselves. On the other hand, the relationship between stroke and PAD is poorly understood. Case-control and population based study of incidence. Place and time: Asturias, Spain, 1990-1992. Dependent variable: stroke, defined according to WHO criteria. PAD, defined according to clinical symptoms of intermittent claudication. Confounding potentials: age, sex, alcohol, smoking, arterial hypertension, hyperglycemia, heart disease. Analysis methods: bivariant comparisons and multivariant analysis by the logistic regression model. 458 cases and 470 controls. PAD was associated with total stroke (OR: 3.4; 95% CI 1.7-7.3), cerebral infarction (OR: 3.2; 95% CI 1.5-6.8), cortical infarction (OR: 3.1; 95% CI 1.3-7.7) and intracerebral hemorrhage (5.0 95% CI 2.0-12.3) once adjusted for risk factors of these diseases. No association was found between small deep infarction and PAD. The association between stroke and PAD possibly denotes similar substrates ...Continue Reading

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