The Association between Apolipoprotein A-II and Metabolic Syndrome in Korean Adults: A Comparison Study of Apolipoprotein A-I and Apolipoprotein B.

Diabetes & Metabolism Journal
Dong Won YiYang Ho Kang

Abstract

Apolipoprotein A-II (apoA-II) is the second-most abundant apolipoprotein in human high-density lipoprotein and its role in cardio metabolic risk is not entirely clear. It has been suggested to have poor anti-atherogenic or even pro-atherogenic properties, but there are few studies on the possible role of apoA-II in Asian populations. The aim of this study is to evaluate the role of apoA-II in metabolic syndrome (MetS) compared with apolipoprotein A-I (apoA-I) and apolipoprotein B (apoB) in Korean adults. We analyzed data from 244 adults who visited the Center for Health Promotion in Pusan National University Yangsan Hospital for routine health examinations. The mean apoB level was significantly higher, and the mean apoA-I level was significantly lower, in MetS; however, there was no significant difference in apoA-II levels (30.5±4.6 mg/dL vs. 31.2±4.6 mg/dL, P=0.261). ApoA-II levels were more positively correlated with apoA-I levels than apoB levels. ApoA-II levels were less negatively correlated with homocysteine and high sensitivity C-reactive protein levels than apoA-I levels. The differences in MetS prevalence from the lowest to highest quartile of apoA-II were not significant (9.0%, 5.7%, 4.9%, and 6.6%, P=0.279). The rela...Continue Reading

References

Jun 1, 1992·Arteriosclerosis and Thrombosis : a Journal of Vascular Biology·H J ParraG Luc
Jan 15, 1987·Biochemical and Biophysical Research Communications·R BarbarasG Ailhaud
Nov 1, 1987·Atherosclerosis·P PuchoisJ C Fruchart
Jun 1, 1996·Arteriosclerosis, Thrombosis, and Vascular Biology·H O MowriW Patsch
Dec 15, 2000·European Journal of Clinical Investigation·P M SweetnamJ W Yarnell
Jul 18, 2002·Atherosclerosis·Anne TailleuxVéronique Clavey
May 30, 2003·Nutrition, Metabolism, and Cardiovascular Diseases : NMCD·G Roselli della RovereE Manzato
Apr 25, 2006·Journal of Internal Medicine·P J Barter, K-A Rye
Dec 5, 2006·The Journal of Clinical Investigation·Daniel J Rader
Oct 10, 2007·Circulation·Rakesh S BirjmohunS Matthijs Boekholdt
Feb 2, 2008·Nature Reviews. Drug Discovery·Tisha Joy, Robert A Hegele
Mar 28, 2009·Arteriosclerosis, Thrombosis, and Vascular Biology·Marja-Riitta TaskinenUNKNOWN FIELD study investigators

❮ Previous
Next ❯

Citations

Jun 25, 2015·Journal of Diabetes and Its Complications·Fariba KoohdaniElham Zamani
Aug 27, 2014·Journal of Lipid Research·C Roger WhiteG M Anantharamaiah
Jul 15, 2021·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·Vincent G PluimakersSebastian J C M M Neggers

❮ Previous
Next ❯

Software Mentioned

SPSS

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Journal of Cosmetic and Laser Therapy : Official Publication of the European Society for Laser Dermatology
Ghislaine BeilinFlorence Benichoux
AAOHN Journal : Official Journal of the American Association of Occupational Health Nurses
R Gail HussDavid J Hewitt
© 2022 Meta ULC. All rights reserved